Results 141 to 150 of about 96,642 (272)

Topical treatment with the toll‐like receptor agonist DIMS0150 has potential for lasting relief of symptoms in patients with chronic active ulcerative colitis by restoring glucocorticoid sensitivity

Inflammatory Bowel Diseases, EarlyView., 2012
Abstract Background: Patients with chronic active ulcerative colitis (UC) are regarded as treatment failures and represent an area of high unmet medical need, as normally the only remaining option is colectomy. Methods: We treated a total of eight chronic active severe UC outpatients with the immunomodulatory agent DIMS0150 as an add‐on to current ...
Eugen Musch, Tamim Lutfi, Petra von Stein, Arezou Zargari, Charlotte Admyre, Mouhamad Malek, Robert Löfberg, Oliver D. von Stein   +7 more
wiley   +1 more source

Peptic ulcer and non-steroidal anti-inflammatory agents [PDF]

Gut, 1987
openaire   +3 more sources

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

ESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna, Elia Rigamonti, Raffaele Zannoni, Vittoria Espeli, Giorgio Moschovitis   +4 more
wiley   +1 more source

Kidney status and events preceding death in heart failure: A real‐world nationwide study

European Journal of Heart Failure, EarlyView.
Abstract Aims Chronic kidney disease is a frequent comorbidity in heart failure (HF) patients, affecting prognosis and mortality. This study investigates the relationship between kidney function and adverse kidney events preceding death in HF patients. Methods and results We analysed registry data of HF patients who died between 2014 and 2021, with at ...
Deewa Zahir Anjum, Caroline Hartwell Garred, Nicholas Carlson, Emil Fosbol, Mariam Elmegaard, Pardeep S. Jhund, John J.V. McMurray, Mark C. Petrie, Lars Kober, Morten Schou   +9 more
wiley   +1 more source

How to handle polypharmacy in heart failure. A clinical consensus statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo, Massimo Iacoviello, Ovidiu Chioncel, Markus S. Anker, Antoni Bayes‐Genis, Frieder Braunschweig, Antonio Cannata, Seif El Hadidi, Gerasimos Filippatos, Pardeep Jhund, Alexandre Mebazaa, Brenda Moura, Massimo Piepoli, Robin Ray, Arsen D. Ristic, Petar Seferovic, Maggie Simpson, Hadi Skouri, Carlo Gabriele Tocchetti, Sophie Van Linthout, Cristiana Vitale, Maurizio Volterrani, Kalliopi Keramida, Sven Wassmann, Basil S. Lewis, Marco Metra, Giuseppe M.C. Rosano, Gianluigi Savarese   +27 more
wiley   +1 more source

Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
Finerenone and glycaemic status in patients with heart failure with mildly reduced/preserved ejection fraction. CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; RR, rate ratio. Abstract Aims The efficacy and safety of the non‐steroidal mineralocorticoid receptor antagonist, finerenone, have not been examined in patients
Jawad H. Butt, Pardeep S. Jhund, Alasdair D. Henderson, Brian L. Claggett, Akshay S. Desai, Carolyn S.P. Lam, Meike Brinker, Patrick Schloemer, Prabhakar Viswanathan, Andrea Lage, Katja Rohwedder, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Muthiah Vaduganathan, Scott D. Solomon, John J.V. McMurray   +18 more
wiley   +1 more source

State-of-the-Art Review on the Treatment of Axial Spondyloarthritis. [PDF]

Med Sci (Basel)
Kaltsonoudis E, Karagianni P, Memi T, Pelechas E.   +3 more
europepmc   +1 more source

Causal association between non-steroidal anti-inflammatory drugs use and the risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study. [PDF]

BMC Med Genomics
Peng ZH, Li MR, He MX, Liu J, Dou JH, Wang YW, Dong Y, Yan C, Li ZH, Chong T, Li ZL.   +10 more
europepmc   +1 more source

Delayed cardiac consequences unveiled by magnetic resonance imaging in a high‐voltage electric shock survivor

ESC Heart Failure, EarlyView.
Golnaz Houshmand, Majid Sadeghpour, Faezeh Tabesh   +2 more
wiley   +1 more source

The use of steroids in adult epilepsy: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective The objective of this study is to systematically review the clinical studies investigating the use of steroids in adult epilepsy. Methods This systematic review utilized Preferred Reporting Items for Systematic Review and Meta‐analysis Protocols (PRISMA‐P) to examine literature on the use of steroids in adult epilepsy.
Ruth Walsh, Colin P. Doherty, Elisabeth Doran   +2 more
wiley   +1 more source