Results 161 to 170 of about 96,642 (272)

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source

Comparative Study of Functional Outcome of Intra-articular Injection of Platelet-Rich Plasma versus Corticosteroid in Treatment of Osteoarthritis of Knee. [PDF]

J Orthop Case Rep
Shaji A, Pradeep E, Kumar KVA, Kumar SD, Mohideen S, Ashwin VY.   +5 more
europepmc   +1 more source

Severe relapse after cessation of immunosuppressive therapy in a patient with co‐occurrence of neuromyelitis optica spectrum disorder and Sjögren's syndrome: A case report

Ibrain, EarlyView.
We report a girl with a diagnosis of “neuromyelitis optica spectrum disorder comorbid Sjogren's syndrome” whose condition showed significant improvement after treatment with corticosteroids and immunosuppressive drugs (prednisolone, hydroxychloroquine, and mycophenolate mofetil).
Man‐Min Zhu, Zu‐Cai Xu, Chang‐Yin Yu, Hao Huang   +3 more
wiley   +1 more source

The effect of a non-steroidal anti-inflammatory drug on the locomotor activity of reindeer (Rangifer tarandus tarandus) on their natural pastures after clamp castration-a pilot study. [PDF]

Acta Vet Scand
Nurmi H, Hänninen L, Laaksonen S, Valros A.   +3 more
europepmc   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, EarlyView.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Immunomodulator Stockpiling as a Means of Broad Defense From Biological Threats. [PDF]

Crit Care Explor
Adalja AA, Inglesby TV.
europepmc   +1 more source

TNF signature in advanced melanoma patients treated with immune checkpoint inhibitors: Results from the MELANFα clinical study

International Journal of Cancer, EarlyView.
What's New? Tumor necrosis factor (TNF) can promote tumor resistance to immune checkpoint inhibitors (ICIs), which are now the standard treatment for advanced melanoma patients. Here, in an advanced melanoma patient cohort, TNF was investigated for a possible predictive relationship with ICI response. Assessments show that after 12 weeks of ICI therapy,
Mathieu Virazels, Amélie Lusque, Stéphanie Brayer, Matthieu Genais, Carine Dufau, Jean Milhès, Thomas Filleron, Cécile Pagès, Vincent Sibaud, Laurent Mortier, Olivier Dereure, Maha Ayyoub, Amandine Fabre, Nathalie Andrieu‐Abadie, Vera Pancaldi, Céline Colacios, Nicolas Meyer, Bruno Ségui, Anne Montfort   +18 more
wiley   +1 more source

Systematic review and meta-analysis of pain management after tonsillectomy. [PDF]

Sci Rep
Geißler K, Scham D, Meißner W, Schlattmann P, Guntinas-Lichius O.   +4 more
europepmc   +1 more source

The role of heat shock proteins in placental ischemic disease: A narrative review of the current literature

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pre‐eclampsia, placental abruption, and fetal growth restriction (FGR) are collectively referred to as placental ischemic disease (PID). Heat shock proteins (HSPs), originally considered as a response to the heat shock, have a central role in regulating the cellular functions by quality controlling the newly synthesized proteins.
Athina A. Samara, Anastasios Lafioniatis, Maria Ioannou, Sofia Tsiapakidou, Angeliki Gerede, Eleftherios Anastasakis, Alexandros Daponte, Sotirios Sotiriou   +7 more
wiley   +1 more source

Topical imiquimod and in situ vulvar melanoma: A promising therapy?

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Vulvar melanoma is a rare type of cancer that affects mainly postmenopausal women. There are no established protocols for the treatment of vulvar melanoma. From data extrapolated from the literature on cutaneous melanoma, surgical excision remains the best option for the resectable disease.
Francesca Pepe, Flavia Silvestri, Eleonora Petra Preti, Anna Daniela Iacobone, Gianluigi Radici, Sabina Vaccari, Paola Queirolo, Giulio Tosti   +7 more
wiley   +1 more source