Primary non-response in inflammatory arthritis treated with biologics and targeted therapies in daily clinical practice. [PDF]
Leon L+7 more
europepmc +1 more source
Abstract Oral ibuprofen is the preferred pharmacotherapeutic option for treatment of a persistent patent ductus arteriosus (PDA), but evidence for its optimal use in extremely low gestational age newborns (ELGANs) remains limited. In the current study, we aimed to investigate the pharmacokinetics and exposure‐response relationship of oral ibuprofen in ...
Mohd Asif+6 more
wiley +1 more source
A New Era in Diabetic Kidney Disease Treatment: The Four Pillars and Strategies to Build Beyond. [PDF]
Han S, Kim S.
europepmc +1 more source
Cardiovascular disease risk in Korean patients with systemic lupus erythematosus compared to diabetes mellitus and the general population. [PDF]
Han JY+6 more
europepmc +1 more source
Effect of Phenylbutazone Administration on Insulin Sensitivity in Horses With Insulin Dysregulation. [PDF]
Kemp KL+3 more
europepmc +1 more source
Abstract Background The aim of this study was to investigate the potential association between vitamin D deficiency and matrix metalloproteinase‐9 (MMP‐9) levels in gingival crevicular fluid (GCF) across various periodontal health and disease statuses.
Yeşim Ayhan Yıldırım+4 more
wiley +1 more source
Benchmarks for low back pain in general practice in Flanders: electronic audit of INTEGO. [PDF]
Paridaens R+3 more
europepmc +1 more source
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley +1 more source
Methotrexate-related drug reactions on kidneys and liver in rheumatoid arthritis: an analysis of spontaneous reports in EudraVigilance. [PDF]
Khoroshun K+3 more
europepmc +1 more source
Upadacitinib for difficult‐to‐treat paediatric Crohn's disease
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou+3 more
wiley +1 more source