Results 21 to 30 of about 107,786 (286)

Screening of newly synthesized benzofuran [3-2, d] pyrimidine derivatives for anti inflammatory activity

MRIMS Journal of Health Sciences, 2016
Background: Most of the non steroidal anti-inflammatory drugs are not equally effective in all inflammatory conditions especially in chronic conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Somnath Motgi, S Manjunath
doaj   +1 more source

Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers

The Korean Journal of Gastroenterology, 2020
Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu, Kyu-Tae Yoon, Joon Sung Kim   +2 more
doaj   +1 more source

Non-Steroidal Anti-Inflammatory Drugs in Colorectal Cancer Chemoprevention

Cancers, 2021
Simple Summary There is growing evidence from epidemiologic, preclinical and clinical studies suggesting that non-steroidal anti-inflammatory drugs (NSAIDs) play a beneficial role in colorectal cancer chemoprevention.
J. Maniewska, D. Jezewska
semanticscholar   +1 more source

Non-aspirin non-steroidal anti-inflammatory drugs in colorectal cancer: a review of clinical studies

British Journal of Cancer, 2022
Colorectal cancer (CRC) chemoprevention is an area of interest. Non-steroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory agents which have been identified as cancer chemoprevention agents given that inflammation is thought to contribute to ...
F. Zaman, S. Orchard, A. Haydon, J. Zalcberg   +3 more
semanticscholar   +1 more source

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects

Molecules, 2021
The antitumor activity of certain anti-inflammatory drugs is often attributed to an indirect effect based on the inhibition of COX enzymes. In the case of anti-inflammatory prodrugs, this property could be attributed to the parent molecules with ...
Fedora Grande, Francesca Giordano, Maria Antonietta Occhiuzzi, Carmine Rocca, Giuseppina Ioele, Michele De Luca, Gaetano Ragno, Maria Luisa Panno, Bruno Rizzuti, Antonio Garofalo   +9 more
doaj   +1 more source

Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study

BMC Medicine, 2020
Background Cancer patients have a highly increased risk of psychiatric disorders following diagnosis, compared with cancer-free individuals. Inflammation is involved in the development of both cancer and psychiatric disorders.
Kejia Hu, Arvid Sjölander, Donghao Lu, Adam K. Walker, Erica K. Sloan, Katja Fall, Unnur Valdimarsdóttir, Per Hall, Karin E. Smedby, Fang Fang   +9 more
doaj   +1 more source

Nonsteroidal anti-inflammatory therapy: changes on renal function of healthy dogs [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To evaluate the renal function in healthy dogs submitted to nonselective and preferential COX-2 nonsteroidal anti-inflammatory drug (NSAID) therapy.
Marina Borges, Rivaldo Marini Filho, Cecília Braga Laposy, Priscylla Tatiana Chalfun Guimarães-Okamoto, Marina Platzeck Chaves, André Nanny Le Sueur Vieira, Alessandra Melchert   +6 more
doaj   +1 more source

Celecoxib to improve scar quality following acute burn injury: Lessons learned after premature termination of a randomised trial

Burns Open
Background: Pre-clinical studies suggest that non-steroidal anti-inflammatory therapy may reduce acute inflammation and modulate scar formation after burn injury.
Edward Raby, Paul Gittings, Edward Litton, Aaron Berghuber, Dale Wesley Edgar, Jo Camilleri, Kris Owen, Rosemary Kendell, Laurens Manning, Mark Fear, Fiona Melanie Wood   +10 more
doaj   +1 more source

Prodrug Approach: NSAID Conjugates of Platinum Compounds as Anti-Cancer Agents

Iraqi Journal of Pharmaceutical Sciences, 2023
Prodrug based synthetic approach is a very promising area of research to enhance the pharmaco–kinetic and pharmaco-dynamic properties of the drugs with the remarkable reduction of the side effects.
NIJA B
doaj   +1 more source

In Vitro Interactions between Non-Steroidal Anti-Inflammatory Drugs and Antifungal Agents against Planktonic and Biofilm Forms of Trichosporon asahii

PLoS ONE, 2016
Increasing drug resistance has brought enormous challenges to the management of Trichosporon spp. infections. The in vitro antifungal activities of non-steroidal anti-inflammatory drugs (NSAIDs) against Candida spp. and Cryptococcus spp.
Suteng Yang, Yong Liao, Lin Cong, Xuelian Lu, Rongya Yang   +4 more
semanticscholar   +1 more source