Results 21 to 30 of about 97,925 (240)

Refractory Peptic Ulcer Disease [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2019
The eradication of Helicobacter pylori and the widespread use of effective antisecretory therapies, including proton pump inhibitors, have improved the management of peptic ulcer disease. However, in some patients, peptic ulcer disease is refractory to 8
Hyun Lim
doaj   +1 more source

Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]

open access: yes, 2011
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G   +8 more
core   +1 more source

Safety and tolerability of nsaids: focus on aceclofenac

open access: yesМедицинский совет, 2019
The article discusses the main problems of safety of non-steroidal anti-inflammatory agents (NSAIDs). The results of randomized clinical studies, pharmacoepidemiological studies and meta-analyses suggesting higher safety of aceclofenac compared to ...
E. A. Ushkalova   +2 more
doaj   +1 more source

How and why systemic inflammation worsens quality of life in patients with advanced cancer [PDF]

open access: yes, 2017
Introduction: The presence of an innate host systemic inflammatory response has been reported to be a negative prognostic factor in a wide group of solid tumour types in both the operable and advanced setting, both local and distant.
Dolan, Ross D.   +4 more
core   +1 more source

Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]

open access: yes, 2006
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko   +6 more
core   +1 more source

Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers

open access: yesThe Korean Journal of Gastroenterology, 2020
Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu   +2 more
doaj   +1 more source

Choosing and using non-steroidal anti-inflammatory drugs in haemophilia [PDF]

open access: yes, 2016
The management of pain and inflammation in haemophilic arthropathy is challenging due to the lack of anti-inflammatory analgesic agents perfectly suitable for this population.
Baigent   +75 more
core   +1 more source

Screening of newly synthesized benzofuran [3-2, d] pyrimidine derivatives for anti inflammatory activity

open access: yesMRIMS Journal of Health Sciences, 2016
Background: Most of the non steroidal anti-inflammatory drugs are not equally effective in all inflammatory conditions especially in chronic conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Somnath Motgi, S Manjunath
doaj   +1 more source

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects

open access: yesMolecules, 2021
The antitumor activity of certain anti-inflammatory drugs is often attributed to an indirect effect based on the inhibition of COX enzymes. In the case of anti-inflammatory prodrugs, this property could be attributed to the parent molecules with ...
Fedora Grande   +9 more
doaj   +1 more source

Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]

open access: yes, 2019
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V.   +4 more
core   +1 more source

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