Safety and tolerability of nsaids: focus on aceclofenac
Медицинский совет, 2019 The article discusses the main problems of safety of non-steroidal anti-inflammatory agents (NSAIDs). The results of randomized clinical studies, pharmacoepidemiological studies and meta-analyses suggesting higher safety of aceclofenac compared to ...
E. A. Ushkalova +2 more
doaj +1 more source
Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]
, 2012 Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Juhász Viktor +36 more
core +1 more source
Synthesis of curcumin derivatives containing non-steroidal anti-inflammatory drugs [PDF]
, 2023 Synthesis and biological evaluation of hybrid molecules combining naturally occurring antioxidant active structures with anti-inflammatory agents has been a strong trend in medicinal chemistry.
Katarzyna Sowa-Kasprzak +4 more
core +1 more source
Refractory Peptic Ulcer Disease [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2019 The eradication of Helicobacter pylori and the widespread use of effective antisecretory therapies, including proton pump inhibitors, have improved the management of peptic ulcer disease. However, in some patients, peptic ulcer disease is refractory to 8
Hyun Lim
doaj +1 more source
Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease
The Korean Journal of Gastroenterology, 2016 Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation.
Young Kwang Shim, Nayoung Kim
doaj +1 more source
Toxic effects of non-steroidal anti-inflammatory agents in rats [PDF]
, 2009 The toxicosis of some non-steroidal anti-inflammatory drugs, piroxicam, indomethacin, phenylbutazone, and aspirin, which occasionally are locally used in Nigeria as rodenticides have been evaluated in rats using changes in the serum biochemical and ...
Taiwo, V.O. +5 more
core +4 more sources
Anti-Inflammatory Drugs as Anticancer Agents [PDF]
, 2020 Inflammation is strictly associated with cancer and plays a key role in tumor development and progression. Several epidemiological studies have demonstrated that inflammation can predispose to tumors, therefore targeting inflammation and the molecules ...
Giovanni Francesco Nicoletti +7 more
core +3 more sources
Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers
The Korean Journal of Gastroenterology, 2020 Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu +2 more
doaj +1 more source
The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]
, 1964 1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core +1 more source
Topical diclofenac: Clinical effectiveness and current uses in osteoarthritis of the knee and soft tissue injuries [PDF]
, 2008 Background: Diclofenac is a commonly used non-steroidal anti-inflammatory drug (NSAID) for symptom control in osteoarthritis (OA) of the knee and soft tissue injuries.
Banning, M
core +1 more source