Results 21 to 30 of about 13,455,088 (254)

Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs) : a systematic structured review of the literature [PDF]

, 2007
Adverse events triggered by non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common drug-related intolerance reactions in medicine; they are possibly related to inhibition of cyclooxygenase-1.
Weberschock, Tobias Bernd Bernd, Boehncke, Wolf-Henning, Tobias Bernd Weberschock, Sylke-Monina Müller, Sandra Boehncke, Müller, Sylke-Monina, Wolf-Henning Boehncke, Weberschock, Tobias Bernd, Boehncke, Sandra   +8 more
core   +1 more source

Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease

The Korean Journal of Gastroenterology, 2016
Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation.
Young Kwang Shim, Nayoung Kim
doaj   +1 more source

Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers

The Korean Journal of Gastroenterology, 2020
Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu, Kyu-Tae Yoon, Joon Sung Kim   +2 more
doaj   +1 more source

Screening of newly synthesized benzofuran [3-2, d] pyrimidine derivatives for anti inflammatory activity

MRIMS Journal of Health Sciences, 2016
Background: Most of the non steroidal anti-inflammatory drugs are not equally effective in all inflammatory conditions especially in chronic conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Somnath Motgi, S Manjunath
doaj   +1 more source

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

, 2012
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Juhász Viktor, István Koncz, Biliczki, Péter, Kristóf Attila, Virág, László, Viktor Juhász, Papp Gyula, Papp Julius Gy, Szél Tamás, Varró András, Kristóf, Attila, Norbert Jost, András Varró, Attila Kristóf, Baczkó István, Virág László, Kohajda, Zsófia, László Virág, Husti, Zoltán, Juhász, Viktor, Zsófia Kohajda, Baczkó, István, Kohajda Zsófia, Biliczki Péter, Julius Gy Papp, Jost Norbert László, Jost, Norbert, Husti Zoltán, Varró, András, Tamás Szél, Jost Norbert, Koncz István, Péter Biliczki, Szél, Tamás, István Baczkó, Papp, Gyula, Zoltán Husti   +36 more
core   +2 more sources

Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study

BMC Medicine, 2020
Background Cancer patients have a highly increased risk of psychiatric disorders following diagnosis, compared with cancer-free individuals. Inflammation is involved in the development of both cancer and psychiatric disorders.
Kejia Hu, Arvid Sjölander, Donghao Lu, Adam K. Walker, Erica K. Sloan, Katja Fall, Unnur Valdimarsdóttir, Per Hall, Karin E. Smedby, Fang Fang   +9 more
doaj   +1 more source

Celecoxib to improve scar quality following acute burn injury: Lessons learned after premature termination of a randomised trial

Burns Open
Background: Pre-clinical studies suggest that non-steroidal anti-inflammatory therapy may reduce acute inflammation and modulate scar formation after burn injury.
Edward Raby, Paul Gittings, Edward Litton, Aaron Berghuber, Dale Wesley Edgar, Jo Camilleri, Kris Owen, Rosemary Kendell, Laurens Manning, Mark Fear, Fiona Melanie Wood   +10 more
doaj   +1 more source

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects

Molecules, 2021
The antitumor activity of certain anti-inflammatory drugs is often attributed to an indirect effect based on the inhibition of COX enzymes. In the case of anti-inflammatory prodrugs, this property could be attributed to the parent molecules with ...
Fedora Grande, Francesca Giordano, Maria Antonietta Occhiuzzi, Carmine Rocca, Giuseppina Ioele, Michele De Luca, Gaetano Ragno, Maria Luisa Panno, Bruno Rizzuti, Antonio Garofalo   +9 more
doaj   +1 more source

Effect of Parecoxib and transversus abdominis plane block on postoperative anxiety and cognition: A randomized controlled-trial

Journal of the Pakistan Medical Association
Objective: To investigate the impact of parecoxib and transversus abdominis plane block on postoperative anxiety and early cognitive function in patients undergoing laparoscopic intestinal surgery.
Fuzhen Zhang, Chengzhi Wang, Kan Li, Xingyuan Cheng, Chenxue Meng, Rongtian Kang   +5 more
doaj   +1 more source

Prodrug Approach: NSAID Conjugates of Platinum Compounds as Anti-Cancer Agents

Iraqi Journal of Pharmaceutical Sciences, 2023
Prodrug based synthetic approach is a very promising area of research to enhance the pharmaco–kinetic and pharmaco-dynamic properties of the drugs with the remarkable reduction of the side effects.
NIJA B
doaj   +1 more source