Synthesis and anti-inflammatory evaluation of novel thiadiazol derivatives of Mefenamic acid
In the search for new potential non-steroidal anti-inflammatory agents, some novel Mefenamic acid derivatives were synthesized and confirmed by spectroscopic data.
A. Ahmadi
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Epidemiology of non-steroidal anti-inflammatory drugs consumption in Spain. The MCC-Spain study [PDF]
This work was partially funded by the “Accion Transversal del Cancer”, approved on the Spanish Ministry Council on the 11th October 2007; The Instituto de Salud Carlos III-FEDER [PI08/1770, PI08/0533, PI08/1359, PI09/00773-Cantabria, PI09/01286-León ...
De Pedro, M. +4 more
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Refractory Peptic Ulcer Disease [PDF]
The eradication of Helicobacter pylori and the widespread use of effective antisecretory therapies, including proton pump inhibitors, have improved the management of peptic ulcer disease. However, in some patients, peptic ulcer disease is refractory to 8
Hyun Lim
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Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease
Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation.
Young Kwang Shim, Nayoung Kim
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Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
A Farkas +56 more
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Safety and tolerability of nsaids: focus on aceclofenac
The article discusses the main problems of safety of non-steroidal anti-inflammatory agents (NSAIDs). The results of randomized clinical studies, pharmacoepidemiological studies and meta-analyses suggesting higher safety of aceclofenac compared to ...
E. A. Ushkalova +2 more
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Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers
Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract ...
Seong Jun Chu +2 more
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Selective glucocorticoid receptor-activating adjuvant therapy in cancer treatments [PDF]
Although adverse effects and glucocorticoid resistance cripple their chronic use, glucocorticoids form the mainstay therapy for acute and chronic inflammatory disorders, and play an important role in treatment protocols of both lymphoid malignancies and ...
Beck, Ilse +5 more
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Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G +8 more
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Background: Most of the non steroidal anti-inflammatory drugs are not equally effective in all inflammatory conditions especially in chronic conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Somnath Motgi, S Manjunath
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