Results 31 to 40 of about 96,395 (289)

Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects

Molecules, 2021
The antitumor activity of certain anti-inflammatory drugs is often attributed to an indirect effect based on the inhibition of COX enzymes. In the case of anti-inflammatory prodrugs, this property could be attributed to the parent molecules with ...
Fedora Grande, Francesca Giordano, Maria Antonietta Occhiuzzi, Carmine Rocca, Giuseppina Ioele, Michele De Luca, Gaetano Ragno, Maria Luisa Panno, Bruno Rizzuti, Antonio Garofalo   +9 more
doaj   +1 more source

Toxic effects of non-steroidal anti-inflammatory agents in rats [PDF]

African Journal of Biomedical Research, 2009
The toxicosis of some non-steroidal anti-inflammatory drugs, piroxicam,indomethacin, phenylbutazone, and aspirin, which occasionally arelocally used in Nigeria as rodenticides have been evaluated in rats usingchanges in the serum biochemical and haematological parameters asindices of toxicity.
Abatan, M.O., Lateef, I., Taiwo, V.O.
openaire   +3 more sources

Choosing and using non-steroidal anti-inflammatory drugs in haemophilia [PDF]

, 2016
The management of pain and inflammation in haemophilic arthropathy is challenging due to the lack of anti-inflammatory analgesic agents perfectly suitable for this population.
Baigent, Biere-Rafi, Braden, Brown, Button, Cagnoni, Caldwell, Castellsague, Chen, Crofford, Curhan, Daly, de Abajo, Dolan, Dworzynski, Eyster, FitzGerald, Forbes, Forman, Fransen van de Putte, Garcia-Poza, Gisbert, Gonzalez-Perez, Grosser, Hallas, Harirforoosh, Hawkey, Hinz, Holstein, Huerta, Hunt, Hunt, Huntjens, Inwood, Jansen, Kamphuisen, Kearney, Konkle, Kulkarni, Kulkarni, Laine, Lanas, Lanas, Lanza, Lin, Makris, Mannucci, Masso Gonzalez, McGettigan, Mittal, Odom, Ofman, Papatheodoridis, Park, Patrignani, Pergantou, Rattray, Riley, Rostom, Scarpignato, Scarpignato, Scarpignato, Schulman, Segasothy, Segasothy, Solomon, Soucie, Srivastava, Stephensen, Steven, Trelle, Tuskey, Van, White, Yeomans, Young   +75 more
core   +1 more source

Celecoxib to improve scar quality following acute burn injury: Lessons learned after premature termination of a randomised trial

Burns Open
Background: Pre-clinical studies suggest that non-steroidal anti-inflammatory therapy may reduce acute inflammation and modulate scar formation after burn injury.
Edward Raby, Paul Gittings, Edward Litton, Aaron Berghuber, Dale Wesley Edgar, Jo Camilleri, Kris Owen, Rosemary Kendell, Laurens Manning, Mark Fear, Fiona Melanie Wood   +10 more
doaj   +1 more source

Prodrug Approach: NSAID Conjugates of Platinum Compounds as Anti-Cancer Agents

Iraqi Journal of Pharmaceutical Sciences, 2023
Prodrug based synthetic approach is a very promising area of research to enhance the pharmaco–kinetic and pharmaco-dynamic properties of the drugs with the remarkable reduction of the side effects.
NIJA B
doaj   +1 more source

Medication use by early-stage breast cancer survivors: a 1-year longitudinal study. [PDF]

, 2016
PurposeThe aim of this study is to characterize the patterns of medication use by early-stage breast cancer (ESBC) survivors from diagnosis to 1 year post-chemotherapy.MethodsA single-center longitudinal study was conducted with ESBC patients diagnosed ...
Chan, Alexandre, Lee, Chee Ping, Loh, Kep Yong, Ng, Raymond, Ng, Terence   +4 more
core   +1 more source

Peritoneal adhesions after laparoscopic gastrointestinal surgery [PDF]

, 2014
Although laparoscopy has the potential to reduce peritoneal trauma and post-operative peritoneal adhesion formation, only one randomized controlled trial and a few comparative retrospective clinical studies have addressed this issue.
MAIS, VALERIO
core   +1 more source

Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]

, 2006
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko, Erdeljić, Viktorija, Francetić, Igor, Huić, Mirjana, Macolić Šarinić, Viola, Makar-Aušperger, Ksenija, Merčep, Iveta   +6 more
core   +1 more source

Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study

BMC Medicine, 2020
Background Cancer patients have a highly increased risk of psychiatric disorders following diagnosis, compared with cancer-free individuals. Inflammation is involved in the development of both cancer and psychiatric disorders.
Kejia Hu, Arvid Sjölander, Donghao Lu, Adam K. Walker, Erica K. Sloan, Katja Fall, Unnur Valdimarsdóttir, Per Hall, Karin E. Smedby, Fang Fang   +9 more
doaj   +1 more source

Gastroprotective effects of oral nucleotide administration [PDF]

, 2006
BACKGROUND AND AIMS: Nucleotides form the building blocks of DNA and are marketed as dietary supplements, alone or in combination with other ingredients, to promote general health.
Belo, A, Fitzgerald, A, Ghosh, S, Marchbank, T, Playford, RJ   +4 more
core   +2 more sources