Results 31 to 40 of about 96,642 (272)
Toxic effects of non-steroidal anti-inflammatory agents in rats [PDF]
African Journal of Biomedical Research, 2009 The toxicosis of some non-steroidal anti-inflammatory drugs, piroxicam,indomethacin, phenylbutazone, and aspirin, which occasionally arelocally used in Nigeria as rodenticides have been evaluated in rats usingchanges in the serum biochemical and haematological parameters asindices of toxicity.
Abatan, M.O., Lateef, I., Taiwo, V.O.
openaire +3 more sources
Gut and Liver, 2013 The mucosa of the gastrointestinal (GI) tract exhibits hydrophobic, nonwettable properties that protect the underlying epithelium from gastric acid and other luminal toxins.
doaj +1 more source
Advanced Biology, EarlyView.The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua +5 more
wiley +1 more source
Nonsteroidal anti-inflammatory therapy: changes on renal function of healthy dogs [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To evaluate the renal function in healthy dogs submitted to nonselective and preferential COX-2 nonsteroidal anti-inflammatory drug (NSAID) therapy.
Marina Borges +6 more
doaj +1 more source
Cooperative Heterogeneous Deep Reinforcement Learning [PDF]
arXiv, 2020 Numerous deep reinforcement learning agents have been proposed, and each of them has its strengths and flaws. In this work, we present a Cooperative Heterogeneous Deep Reinforcement Learning (CHDRL) framework that can learn a policy by integrating the advantages of heterogeneous agents.
arxiv
Advanced Healthcare Materials, EarlyView.Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia +9 more
wiley +1 more source
Molecular and cellular paradigms of multidrug resistance in cancer
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya +6 more
wiley +1 more source
A case of delayed maculopapular eruption to ibuprofen and acute urticaria to acetaminophen
SAGE Open Medical Case Reports, 2021 We present the unique case of a 33-year-old male referred to our clinic in search of analgesic options who was found to have a delayed hypersensitivity reaction to ibuprofen manifesting as a maculopapular rash and acute urticaria to acetaminophen.
Jason Wong +3 more
doaj +1 more source
Lichenoid drug eruption induced by teriflunomide
Annals of Indian Academy of Neurology, 2023 Lichenoid drug eruptions are a type of skin reaction that is caused by medication and mimics idiopathic lichen planus. Various medications have been known to cause lichenoid drug eruptions, such as antibiotics, anti-convulsants, anti-diabetics, anti ...
Fatima-Zahra Agharbi +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A new dual‐layer hydrogel barrier for preventing postoperative abdominal adhesions is developed. The inner layer, consisting of polyethyleneimine (PEI) and thioctic acid (TA), enhanced adhesion to moist tissues. The outer layer combines zwitterionic, thermoresponsive hyaluronic acid with anti‐inflammatory epigallocatechin gallate (EGCG) and forms a ...
Mena Asha Krishnan +6 more
wiley +1 more source