Results 101 to 110 of about 822,039 (299)
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
The pro- and anti-inflammatory properties of the cytokine interleukin-6
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011 Interleukin-6 is a cytokine not only involved in inflammation and infection responses but also in the regulation of metabolic, regenerative, and neural processes. In classic signaling, interleukin-6 stimulates target cells via a membrane bound interleukin-6 receptor, which upon ligand binding associates with the signaling receptor protein gp130.
Scheller, Jürgen +3 more
openaire +2 more sources
Медицинская иммунологияThe immunomodulatory properties of probiotics largely depend on the metabolites secreted into the culture medium, which is studied as a cell-free supernatant and referred to as postbiotics. The aim of the present work was to conduct screening of cytokine
O. V. Bukharin +5 more
doaj +1 more source
, 2011 Improving understanding of how inflammatory responses by monocytes and macrophages are regulated may aid in the development of more targeted therapies for chronic inflammatory disease.
Woodward, Eleanor
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Pro-inflammatory and Anti-inflammatory Cytokines 5 days post-CLP.
, 2016 Pro-inflammatory and Anti-inflammatory Cytokines 5 days post-CLP.
Max Vaickus (3138531) +3 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
FEATURES OF CYTOKINE-MEDIATED REGULATION OF FOCAL AND SYSTEMIC INFLAMMATION IN COPD
Медицинская иммунология, 2014 Chronic obstructive pulmonary disease (COPD) is associated with pulmonary and systemic inflammation. The latter is likely to contribute significantly to the pathobiology of numerous extrapulmonary effects of the disease, i.e., systemic effects of COPD ...
E. A. Surkova +3 more
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Mediadores químicos e resposta celular na colite induzida pelo DSS: papel dos mediadores lipídicos derivados do omega-3 na resolução da colite experimental [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaAs doenças inflamatórias intestinais (IBD) representam um grupo de disfunções do trato gastrointestinal, que acometem ...
Bento, Allisson Freire
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