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Pro-inflammatory Cytokines, Ferroptosis, and Cancer. [PDF]
Acta NaturaeFerroptosis, iron-dependent regulated cell death, is induced by the polyunsaturated fatty acid peroxidation of membrane phospholipids and is controlled by glutathione peroxidase 4. In recent years, convincing evidence has emerged, demonstrating a close relationship between chemo-, radio-, immuno-, and targeted therapy resistance and ferroptosis ...
Vartanian AA, Kosorukov VS.
europepmc +3 more sources
Pro-inflammatory cytokines as potential predictors for intradialytic hypotension [PDF]
Renal Failure, 2021 Intradialytic hypotension (IDH) is a common complication in maintaining hemodialysis (MHD) patients. Immune activation might be part of the mechanisms. However, the association between pro-inflammatory cytokines and blood pressure (BP) has not been deeply explored.
Jinbo Yu, Xuesen Cao, Bo Shen
exaly +4 more sources
Pro-Inflammatory Cytokines and MicroRNAs in Male Infertility [PDF]
Molecular Biology Reports, 2021 Abstract Background: Male infertility is a problem that affects 10-15% of men of reproductive age. In particular, gametogenesis is a complex process in which inflammation may play a central role through the secretion of cytokines and the expression of microRNAs. We assessed the potential role of proinflammatory cytokines (TNF-α, IL-6 and IL-1α)
Hana Attia +7 more
openaire +3 more sources
Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines [PDF]
Open Biology, 2020 Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; disease prognosis is influenced mainly by multi-organ involvement. Acute respiratory distress syndrome, heart failure, renal failure, liver damage, shock and multi-organ ...
Fara, Antonella +3 more
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Pro-inflammatory Cytokines in Acute Coronary Syndromes
Current Pharmaceutical Design, 2020 Background:Over the last decades, the role of inflammation and immune system activation in the initiation and progression of coronary artery disease (CAD) has been established.Objectives:The study aimed to present the interplay between cytokines and their actions preceding and shortly after ACS.Methods:We searched in a systemic manner the most relevant
Mourouzis, K. +9 more
openaire +3 more sources
Pro-inflammatory cytokines and adipose tissue [PDF]
Proceedings of the Nutrition Society, 2001 Cytokines appear to be major regulators of adipose tissue metabolism. Therapeutic modulation of cytokine systems offers the possibility of major changes in adipose tissue behaviour. Cytokines within adipose tissue originate from adipocyte, preadipocyte and other cell types.
openaire +2 more sources
Immunomodulation of autoimmune arthritis by pro-inflammatory cytokines [PDF]
Cytokine, 2017 Pro-inflammatory cytokines promote autoimmune inflammation and tissue damage, while anti-inflammatory cytokines help resolve inflammation and facilitate tissue repair. Over the past few decades, this general feature of cytokine-mediated events has offered a broad framework to comprehend the pathogenesis of autoimmune and other immune-mediated diseases,
Eugene Y, Kim, Kamal D, Moudgil
openaire +2 more sources
Regulation of autoimmune inflammation by pro-inflammatory cytokines [PDF]
Immunology Letters, 2008 The pro-inflammatory cytokines play a critical role in the initiation and propagation of autoimmune arthritis and many other disorders resulting from a dysregulated self-directed immune response. These cytokines influence the interplay among the cellular, immunological and biochemical mediators of inflammation at multiple levels.
Eugene Y, Kim, Kamal D, Moudgil
openaire +2 more sources
Pro-inflammatory cytokines in cryptoglandular anal fistulas [PDF]
Techniques in Coloproctology, 2016 Sphincter-preserving procedures for the treatment of transsphincteric fistulas fail in at least one out of every three patients. It has been suggested that failure is due to ongoing disease in the remaining fistula tract. Cytokines play an important role in inflammation. At present, biologicals targeting cytokines are available.
van Onkelen, R. S. +5 more
openaire +4 more sources
The Pro-Inflammatory Cytokine Cascade [PDF]
, 2002 The production of pro-inflammatory cytokines is a prerequisite for initiating the anti-infectious process, whereas their exacerbated production during severe inflammation may contribute to deleterious consequences. The capacity of interleukin (IL)-l and tumor necrosis factor-alpha (TNF-a) to induce inflammatory mediators contributes to their pro ...
J.-M. Cavaillon, M. Adib-Conquy
openaire +1 more source