Results 11 to 20 of about 3,051,760 (306)

Pro-inflammatory Cytokines in Animal and Human Gestation

Current Pharmaceutical Design, 2010
The story of cytokines in pregnancy began about 30 years ago, approximately in concomitance with the understanding that cytokines are autocrine-paracrine regulators of physiological processes. Pro-inflammatory cytokines are predominant in the early and late events of gestation, e.g.
Ricci, Luana, Bhattacharjee, Jayonta, Bechi, Nicoletta, Romagnoli, Roberta, Jantra, SILKE BIRGIT, Ietta, Francesca   +5 more
openaire   +4 more sources

Pro-Inflammatory Cytokines and MicroRNAs in Male Infertility [PDF]

Molecular Biology Reports, 2021
Abstract Background: Male infertility is a problem that affects 10-15% of men of reproductive age. In particular, gametogenesis is a complex process in which inflammation may play a central role through the secretion of cytokines and the expression of microRNAs. We assessed the potential role of proinflammatory cytokines (TNF-α, IL-6 and IL-1α)
Hana Attia, Federica Finocchi, Monia Orciani, Meriem Mehdi, Ines Zidi Jrah, Raffaella Lazzarini, Giancarlo Balercia, Monica Mattioli Belmonte   +7 more
openaire   +3 more sources

Pro-inflammatory Cytokines, Ferroptosis, and Cancer. [PDF]

Acta Naturae
Ferroptosis, iron-dependent regulated cell death, is induced by the polyunsaturated fatty acid peroxidation of membrane phospholipids and is controlled by glutathione peroxidase 4. In recent years, convincing evidence has emerged, demonstrating a close relationship between chemo-, radio-, immuno-, and targeted therapy resistance and ferroptosis ...
Vartanian AA, Kosorukov VS.
europepmc   +3 more sources

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines [PDF]

Open Biology, 2020
Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; disease prognosis is influenced mainly by multi-organ involvement. Acute respiratory distress syndrome, heart failure, renal failure, liver damage, shock and multi-organ ...
Fara, Antonella, Mitrev, Zan, Rosalia, Rodney Alexander, Assas, Bakri M.   +3 more
openaire   +3 more sources

Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]

, 2010
Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
J.S.H. Vles, Schwarz, J.M., Berfelo, M. W., M. Schwarz, Vles, J. S. H., Schwarz, M., Hulsman, J. A. R. J., A. Myint, Majoie, H. J. M., M.W. Berfelo, Hulsman, J.A.R.J., K. Rijkers, Myint, A., J.A.R.J. Hulsman, Rijkers, K., H.J.M. Majoie   +15 more
core   +1 more source

Pro-inflammatory Cytokines in Acute Coronary Syndromes

Current Pharmaceutical Design, 2020
Background:Over the last decades, the role of inflammation and immune system activation in the initiation and progression of coronary artery disease (CAD) has been established.Objectives:The study aimed to present the interplay between cytokines and their actions preceding and shortly after ACS.Methods:We searched in a systemic manner the most relevant
Mourouzis, K., Oikonomou, E., Siasos, G., Tsalamadris, S., Vogiatzi, G., Antonopoulos, A., Fountoulakis, P., Goliopoulou, A., Papaioannou, S., Tousoulis, D.   +9 more
openaire   +3 more sources

Oncogenic pathways activated by pro-inflammatory cytokines promote mutant p53 stability: clue for novel anticancer therapies

, 2020
Inflammation and cancerogenesis are strongly interconnected processes, not only because inflammation promotes DNA instability, but also because both processes are driven by pathways such as NF-kB, STAT3, mTOR and MAPKs.
D'Orazi, Gabriella, Cordani, Marco, Cirone, Mara   +2 more
core   +2 more sources

Role of Pro- and Anti-Inflammatory Cytokines in Rheumatoid Arthritis: Correlation with Disease Activity.

مجلة كلية الطب, 2010
Background: Rheumatoid arthritis (RA) is a chronic and debilitating autoimmune disease characterized by chronic inflammation with subsequent cartilage and bone destruction.
Ahmed A. H. Al-Hassan
doaj   +1 more source

IMMUNO-INFLAMATORY RESPONSE IN ISCHEMIC HEART DISEASE

Рациональная фармакотерапия в кардиологии, 2015
Aim. To estimate the role of immuno-inflammatory response in developing of angina pectoris in patients with ischemic heart disease (IHD).Material and methods: The study included 83 patients with IHD and angina pectoris of functional class (FC) II (30 ...
N. E. Zakirova, N. Kh. Khafizova, I. M. Karamova, A. N. Zakirova, R. G. Oganov   +4 more
doaj   +3 more sources

Assessment of the drug–drug interaction potential for therapeutic proteins with pro‐inflammatory activities

Clinical and Translational Science, 2023
It is well‐recognized that therapeutic proteins (TPs) with pro‐inflammatory activities elevate the pro‐inflammatory cytokines and result in cytokine‐drug interactions. In the current review, several pro‐inflammatory cytokines, including IL‐2, IL‐6, IFN‐γ,
Yanke Yu, Charity Henrich, Diane Wang
doaj   +1 more source