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IgM antibodies against acetylated proteins as a possible starting point of the anti-modified protein antibody response in rheumatoid arthritis

Annals of the Rheumatic Diseases
Thomas Huizinga, Diane van der Woude, Mami Tamai   +2 more
exaly   +4 more sources

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Cross-reactivity of anti-modified protein antibodies in rheumatoid arthritis

Clinical and Experimental Rheumatology
This review comprehensively discusses the cross-reactivity of autoantibodies against modified proteins (AMPAs), the hallmark of rheumatoid arthritis (RA). We found that regardless of tissue sources, subtypes, or isotypes of B cells, AMPAs show high cross-reactivity within and across antigens undergoing citrullination, carbamylation, lysine-acetylation ...
Guangyue, Zhang, Lipu, Yao, Qiyu, Zhu, Martin, Herrmann, Yi, Zhao   +4 more
openaire   +2 more sources

AB0189 Anti-Modified Protein Antibody Response Pattern Influences The Risk for Disease Relapse in Rheumatoid Arthritis Patients Tapering Disease Modifying Anti-Rheumatic Drugs

Annals of the Rheumatic Diseases, 2016
Background Autoimmunity is still present in rheumatoid arthritis patients in sustained disease remission. In the absence of inflammation the pattern of autoimmunity against post-translationally modified proteins could potentially impact the course of disease of rheumatoid arthritis patients, espepcially their risk to experience relapse of disease when
C. Figueiredo, H. Bang, J.F. Cobra, M. Englbrecht, A.J. Hueber, J. Haschka, B. Manger, A. Kleyer, M. Reiser, S. Finzel, H.-P. Tony, S. Kleinert, J. Wendler, F. Schuch, M. Ronneberger, M. Feuchtenberger, M. Fleck, K. Manger, W. Ochs, M. Schmitt-Haendle, H.-M. Lorenz, H. Nuesslein, R. Alten, J.C. Henes, K. Krueger, J. Rech, G. Schett   +26 more
openaire   +1 more source

POS0103 IN RHEUMATOID ARTHRITIS, THE ASSOCIATION BETWEEN ANTI-MODIFIED PROTEIN ANTIBODIES AND LONG-TERM OUTCOMES IS DOMINATED BY THE EFFECT OF ANTI-CITRULLINATED PROTEIN ANTIBODIES

Annals of the Rheumatic Diseases, 2022
T.J. Van Wesemael, M. Verstappen, R. Knevel, A. Van der Helm-van Mil, T. Huizinga, R. Toes, D. Van der Woude   +6 more
openaire   +1 more source

Proteomic analysis in idiopathic pulmonary fibrosis with presence of anti-modified protein antibodies

Airway cell biology and immunopathology, 2023
Dimitrios Kalafatis, Vijay Joshua, Monika Hansson, Linda Mathsson-Alm, Linda Elowsson, Gunilla Westergren-Thorsson, Aase Hensvold, Magnus Sköld   +7 more
openaire   +1 more source

POS1058 CORRELATION BETWEEN SERUM KL-6 AND ANTI-MODIFIED PROTEIN ANTIBODIES (AMPAS) IN RHEUMATOID ARTHRITIS-ASSOCIATED INTERSTITIAL LUNG DISEASE

Annals of the Rheumatic Diseases, 2023
J.C. Sarmiento-Monroy, A. Pérez-Isidro, R. Castellanos Moreira, V. Ruiz, B. Frade-Sosa, A. Azuaga, J. Ramírez, M.J. Gomara, C. Garcia-Moreno, I. Haro, A. Colmenero, M. Morales-Ruiz, E. Ruiz-Ortiz, O. Viñas, F. Hernández-González, J. Sellarés, J.D.D. Cañete, R. Sanmartí, J.A. Gómez-Puerta   +18 more
openaire   +1 more source

From Rheumatoid Factor to Anti-Citrullinated Protein Antibodies and Anti-Carbamylated Protein Antibodies for Diagnosis and Prognosis Prediction in Patients with Rheumatoid Arthritis

International Journal of Molecular Sciences, 2021
Shue-Fen Luo, Huang-Yu Yang, Jenn-Haung Lai   +2 more
exaly  

Anti-citrullinated protein antibodies as biomarkers in rheumatoid arthritis

Expert Review of Molecular Diagnostics, 2023
Gunnar Houen, Nicole Hartwig Trier
exaly  

Could the anti-modified protein antibody concept help better define seronegative rheumatoid arthritis?

Joint Bone Spine
Brevet, Pauline, Fréret, Manuel, Barat, Eric, Lequerré, Thierry, Boyer, Olivier, Vittecoq, Olivier   +5 more
openaire   +3 more sources

Anti-citrullinated protein antibodies are associated with neutrophil extracellular trap formation in rheumatoid arthritis

Journal of Clinical Laboratory Analysis, 2021
Siyu Wu, Wanchan Peng
exaly