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Anti-NMDAR antibodies, the blood–brain barrier, and anti-NMDAR encephalitis

Frontiers in Neurology, 2023
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an antibody-related autoimmune encephalitis. It is characterized by the existence of antibodies against NMDAR, mainly against the GluN1 subunit, in cerebrospinal fluid (CSF). Recent research
Xiarong Gong, Xiarong Gong, Niya Wang, Hongyan Zhu, Ning Tang, Kunhua Wu, Qiang Meng   +6 more
doaj   +5 more sources

RARE MANIFESTATION OF ANTI-NMDAR ENCEPHALITIS

Journal of Ayub Medical College Abbottabad, 2022
N-methyl-d-aspartate receptor (NMDAR) antibody encephalitis is an autoimmune syndrome with the development of antibody production against the NMDAR, affecting synaptic plasticity and cognition. It has a common association with ovarian teratomas with women being affected disproportionately.
Farhan Ali, A. Waseem, Hina Sadiq, Areeba Rehman   +3 more
openalex   +4 more sources

Risk Factors for Mortality in Anti-NMDAR, Anti-LGI1, and Anti-GABABR Encephalitis

Frontiers in Immunology, 2022
ObjectiveWe aimed to investigate the mortality rate and identify the predictors of death in patients with anti-NMDAR, anti-LGI1, and anti-GABABR encephalitis.MethodsPatients with anti-NMDAR, anti-LGI1, and anti-GABABR encephalitis were recruited from the
Rui Zhong, Qingling Chen, Xinyue Zhang, Hanyu Zhang, Weihong Lin   +4 more
doaj   +3 more sources

Screening for anti-NMDAR encephalitis in psychiatry

Journal of Psychiatric Research, 2020
Anti-NMDAR encephalitis most commonly presents to psychiatric services, so early identification of this disorder is essential. We aim to validate the two screening criteria (Scott et al. and Herken and Pruss) which have been proposed to identify first episode psychosis patients who should have anti-NMDAR antibody testing.
Nicola Warren, Joshua Flavell, Cullen O'Gorman   +2 more
exaly   +6 more sources

Anti-NMDAR encephalitis with ovarian teratomas: Review of the literature and two case reports

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is a paraneoplastic syndrome associated with ovarian teratomas. Anti-NMDAR encephalitis patients typically present with prominent psychiatric symptoms, seizures, and involuntary ...
Hsiao-Chen Chiu, Yu-Ching Su, Su-Cheng Huang, Han-Lin Chiang, Pei-Shen Huang   +4 more
doaj   +3 more sources

Case report: anti-NMDAR encephalitis with cerebellar ataxia as the initial manifestation [PDF]

BMC Neurology
Background Among autoimmune encephalitis (AE), anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common type. In patients with anti-NMDAR encephalitis, psychiatric and cognitive symptoms were often observed as the initial manifestations,
Yidi Wang, Linyang Cui, Nan Zhang
doaj   +2 more sources

A CASE SERIES ON ANTI NMDAR ENCEPHALITIS

International Journal of Pharmacy and Pharmaceutical Sciences, 2017
N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune neurological disorder arising from the generation of antibodies which binds to the synaptic proteins. Here we present a case series of 3 cases where the different aspects of treating NMDAR encephalitis are dealt with.
Reshma Reji, Sherin Alexander, Meenu Vijayan   +2 more
openalex   +3 more sources

Relapses in Anti-NMDAR Encephalitis: Clinical Characterization and Predictive Features. [PDF]

Neurol Neuroimmunol Neuroinflamm
During the recovery phase of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, up to 25% of relapses have been reported. Herein, we aimed to clinically characterize these relapses, analyze potential clinical predictors during the first episode, and evaluate the impact of immunotherapy in their occurrence.This was a retrospective observational ...
Ciano-Petersen NL, Villagrán-García M, Muñiz-Castrillo S, Farina A, Vogrig A, Goncalves D, Nicole F, Rogemond V, Picard G, Aubart M, Psimaras D, Oliver B, Serrano-Castro PJ, Joubert B, Honnorat J.   +14 more
europepmc   +4 more sources

Brain astrocytoma misdiagnosed as anti-NMDAR encephalitis: a case report [PDF]

BMC Neurology, 2019
Background Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, which is the most common type of autoimmune encephalitis, is caused by the production of autoantibodies against NMDA receptor.
Jie Lu, Ji-hong Zhang, Ai-liang Miao, Jun-xiong Yin, Dong-lin Zhu, Xing-jian Lin, Dao-wen Chen, Jing-ping Shi   +7 more
doaj   +2 more sources

The gut-brain axis: potential reshaping the future of anti-NMDAR encephalitis treatment [PDF]

Frontiers in Immunology
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a type of autoimmune encephalitis with a high disability rate. However, its pathogenesis remains unclear and warrants further elucidation to facilitate the development of effective treatment ...
Changchang Shen, Yinyin Xie, Yi Xie, Lina Wang, Aoya Han, Xinru Zhou, Shijie Zhang, Xili Fu, Nanchang Xie   +8 more
doaj   +2 more sources