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Autoimmune Encephalitis—A Multifaceted Pathology

Biomedicines, 2023
Autoimmune encephalitis is a complex and multifaceted pathology that involves immune-mediated inflammation of the brain. It is characterized by the body’s immune system attacking the brain tissue, leading to a cascade of inflammatory processes.
Monica Neațu, Ana Jugurt, Anca Covaliu, Eugenia Irene Davidescu, Bogdan Ovidiu Popescu   +4 more
doaj   +4 more sources

Myasthenia gravis complicated with autoimmune encephalitis: a review [PDF]

Frontiers in Neurology
ObjectiveThis review aims to provide updated information about myasthenia gravis (MG) complicated with autoimmune encephalitis.BackgroundMG and autoimmune encephalitis are both antibody-mediated disorders with a need for active and individually adapted ...
Nils Erik Gilhus, Nils Erik Gilhus
doaj   +2 more sources

Choroid Plexus Abnormalities in Autoimmune Encephalitis. [PDF]

CNS Neurosci Ther
Choroid plexus (ChP) enlargement is a robust AE imaging biomarker, with independent prognostic value for AEAE and poor outcomes. ChP MRI radiomic model predicts AEAE well, leveraging shape features to provide effective predictive performance for AEAE. Multi‑omics links ChP enlargement to reduced glutamatergic synapse pathway activity and enhanced PI3K ...
Sun Y, Wang N, Ge S, Feng L, Wang Q.
europepmc   +3 more sources

Predictors for identifying autoimmune encephalitis in pediatric patients [PDF]

Frontiers in Cellular and Infection Microbiology
ObjectivesThis study aimed to identify the independent predictors and develop a predictive model for autoimmune encephalitis (AE) in pediatric populations.MethodsThis retrospective study comprised 88 pediatric patients with encephalitis (37 AE cases and ...
Yanmeng Sun, Yanmeng Sun, Shangmin Yang, Shangmin Yang, Mengyuan Wang, Mengyuan Wang, Huan Xu, Shifu Wang, Shifu Wang   +8 more
doaj   +2 more sources

Serial FDG-PET in probable seronegative autoimmune encephalitis presenting as severe behavioral regression in a child with autism. [PDF]

PCN Rep
Abstract Background Autoimmune encephalitis in children may present with predominant psychiatric and behavioral symptoms, creating diagnostic challenges, particularly in patients with pre‐existing autism spectrum disorder. Seronegative forms are especially difficult to recognize because neuronal autoantibodies are not detected, and diagnostic ...
Guez E, Falempin T, Hanin C, Arbouche A, Boucher R, Hamdi M, Raffin M, Consoli A, Kas A, Giannitelli M, Cohen D.   +10 more
europepmc   +4 more sources

Recurrent Autoimmune Encephalitis in a Patient With Autoimmune Polyendocrine Syndrome Type 1 [PDF]

Case Reports in Critical Care
Autoimmune polyendocrine syndrome Type 1, also known as autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APS-1/APECED), is a rare monogenic autoimmune disorder with increasing recognition of neurologic manifestations.
Jason T. Stemple, Kamal Abulebda, Grace F. Ryan, Nadine G. Haddad, Alden F. Dewey, Jennah C. Foltz, Laurence E. Walsh, Riad Lutfi   +7 more
doaj   +2 more sources

Comparing the efficacy of first-line immunotherapies in autoimmune encephalitis: a scoping review. [PDF]

Front Neurol
Pithia R, Thomas J, Varkey TC.
europepmc   +3 more sources

Immunopathological mechanisms in autoimmune encephalitis: from pathogenesis to targeted therapies [PDF]

Front Immunol
Lu Y, Zhang S, Li H, Yin Q, Fang Y, Zhou P, Qiao S, Xin T.   +7 more
europepmc   +3 more sources

Long-Term Outcomes in Autoimmune Encephalitis: A Nationwide, Clinical Study in Denmark. [PDF]

Neurol Neuroimmunol Neuroinflamm
Gaist TA, Lodahl LR, Thorup HA, Nissen MS, Hansen K, Harbo T, Rekers S, Finke C, Blaabjerg M.   +8 more
europepmc   +3 more sources

Sleep disturbances in autoimmune encephalitis [PDF]

Encephalitis, 2023
Autoimmune encephalitis is an inflammatory neurological disorder characterized by psychiatric symptoms, cognitive impairment, and focal neurological deficits or seizures.
Dae Lim Koo
doaj   +1 more source