Results 261 to 270 of about 1,405,286 (325)

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Dual-targeting CSF1R signaling attenuates neurotoxic myeloid activation and preserves photoreceptors in retinitis pigmentosa. [PDF]

J Neuroinflammation
Wu J, Zhang J, Lin B.
europepmc   +1 more source

Dominant-negative isoform of TDP-43 is regulated by ALS-linked RNA-binding proteins. [PDF]

J Cell Biol
Hasegawa-Ogawa M, Onda-Ohto A, Nakajo T, Funabashi A, Ohya A, Yazaki R, Okano HJ.   +6 more
europepmc   +1 more source

Prenatal valproic acid on the basis of gestational diabetes also induces autistic behavior and disrupts myelination and oligodendroglial maturation slightly in offspring. [PDF]

Transl Psychiatry
Li M, Qiao Z, Li J, Zhou H, Huang D, Cai Y, Li X, Zhang Z, Zhou J, Zhou J.   +9 more
europepmc   +1 more source

Secreted lumican from the tumor microenvironment potentiates HCC stemness and progression. [PDF]

Hepatol Commun
Chan KK, Wong CY, Au KY, Suen LH, Yip WW, Zhang JM, Fung EY, Lee TK, Ng IO, Cheung TT, Lo RC.   +10 more
europepmc   +1 more source

Small Nuclear Ribonucleoprotein Autoantibody Associated With Blood-Nerve Barrier Breakdown in Guillain-Barré Syndrome. [PDF]

Neurol Neuroimmunol Neuroinflamm
Shimizu F, Koga M, Mizukami Y, Watanabe K, Sato R, Takeshita Y, Maeda T, Kanda T, Nakamori M.   +8 more
europepmc   +1 more source