Targeting Inflammation in Obesity and the Cardiovascular-Kidney-Metabolic Syndrome Spectrum: A Narrative Review. [PDF]
Noormandi A +10 more
europepmc +1 more source
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto +8 more
wiley +1 more source
Broussoflavonol F Alleviates Obesity-Associated Metabolic Syndrome in Obese Mice by Modulating Gut Microbiota. [PDF]
Zhao C +5 more
europepmc +1 more source
Redefining Fatty Liver Disease: How Updated Nomenclature Reshapes Clinical Laboratory Diagnostics
The transition from nonalcoholic fatty liver disease (NAFLD) to metabolic dysfunction‐associated steatotic liver disease (MASLD) reorients laboratory diagnosis from exclusion‐based rules toward metabolic and inflammatory biomarkers. This review compares their diagnostic criteria, epidemiology, insulin resistance mechanisms, imaging, and key laboratory ...
Ran Wei +3 more
wiley +1 more source
Pharmacotherapy for Obstructive Sleep Apnea: From Pathophysiology to Emerging Treatments. [PDF]
Zhou R, Yin G, Zhu Y, Sun Y.
europepmc +1 more source
Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia +11 more
wiley +1 more source
Holistic Management of Obesity in Patients with Incidental Cancer After Unprovoked Deep Vein Thrombosis: A Cardiometabolic and Antithrombotic Framework. [PDF]
Geraci C +9 more
europepmc +1 more source
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo +4 more
wiley +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Orphan GPCRs in diabetes mellitus: metabolic control, inflammation, and drug development. [PDF]
Chandrabose S +5 more
europepmc +1 more source

