Results 251 to 260 of about 219,576 (296)

Food Ingredients as Anti-Obesity Agents: A Review

Critical Reviews in Food Science and Nutrition, 2013
Overweight and obesity have a major impact on global health; their prevalence has rapidly increased in all industrialized countries in the past few decades and diabetes and hypertension are their direct consequences. Pharmacotherapy provides reinforcement for obesity treatment, but should be an adjunctive support to diet, exercise, and lifestyle ...
S Pena, Estrella Sayas-Barberá, JOSÉ Angel Pérez-Álvarez   +2 more
exaly   +3 more sources

Anti-Obesity Agents and the US Food and Drug Administration

Current Obesity Reports, 2014
Despite the growing market for obesity care, the US Food and Drug Administration (FDA) has approved only two new pharmaceutical agents-lorcaserin and combination phentermine/topiramate-for weight reduction since 2000, while removing three agents from the market in the same time period. This article explores the FDA's history and role in the approval of
Jeffrey I Mechanick
exaly   +3 more sources

Food Ingredients as Anti-Obesity Agents

Trends in Endocrinology & Metabolism, 2015
Brown adipose tissue (BAT) is a site of adaptive non-shivering thermogenesis after cold exposure, and is involved in the regulation of energy expenditure and body fatness. BAT can be activated and recruited by not only cold exposure but also by various food ingredients including capsaicin in chili pepper and catechins in green tea, which would be ...
Masayuki, Saito, Takeshi, Yoneshiro, Mami, Matsushita   +2 more
openaire   +2 more sources

Biosynthesis and biotechnological production of the anti-obesity agent celastrol

Nature Chemistry, 2023
Obesity is a major health risk still lacking effective pharmacological treatment. A potent anti-obesity agent, celastrol, has been identified in the roots of Tripterygium wilfordii. However, an efficient synthetic method is required to better explore its biological utility.
Yong Zhao, Nikolaj L. Hansen, Yao-Tao Duan, Meera Prasad, Mohammed S. Motawia, Birger L. Møller, Irini Pateraki, Dan Staerk, Søren Bak, Karel Miettinen, Sotirios C. Kampranis   +10 more
openaire   +3 more sources

Resveratrol as Anti-Obesity and Anticancer Agent

2021
Resveratrol is a naturally occurring phytochemical, synthesized against various stress responses like infection, UV radiation, and weather change. It plays an important role in the regulation of various biological processes such as inflammation, cell proliferation, apoptosis, calorie restriction, and lipid deposition.
Vishal Kumar Gupta, Pratishtha Sonker, Ajay Kumar   +2 more
openaire   +1 more source

Dehydroepiandrosterone: An anti‐obesity and anti‐carcinogenic agent

Nutrition and Cancer, 1981
Long-term treatment of female C3H-Avy/A (obese) and C3H-A/A (non-obese) mice with dehydroepiandrosterone, an adrenal steroid found in subnormal levels in women predisposed to develop breast cancer, reduces weight gain without suppressing appetite and significantly inhibits the development of spontaneous breast cancer.
A G, Schwartz, G C, Hard, L L, Pashko, M, Abou-Gharbia, D, Swern   +4 more
openaire   +2 more sources

EGCG as Anti-Obesity and Anticancer Agent

2021
EGCG, the most abundant catechins of green tea exhibits several beneficial impacts on human health and helps in the amelioration of various pathological conditions including cardiovascular diseases, obesity, and cancer. The anti-obesity potential of EGCG depends on its potent antioxidant property, lipid metabolism modulatory action, and adipogenesis ...
Shiv Govind Rawat, Rajan Kumar Tiwari, Pratishtha Sonker, Rajendra Prakash Maurya, Naveen Kumar Vishvakarma, Ajay Kumar   +5 more
openaire   +1 more source

Serotonergic Anti-Obesity Agents

Drugs, 2011
The role of serotonin (5-hydroxytryptamine) in appetite control is long established. Serotonergic manipulations reduce food intake in rodents in a manner consistent with satiety. In humans, drugs such as fenfluramine, dexfenfluramine and sibutramine all reduce energy intake, suppress hunger and enhance satiety.
Jason C G, Halford, Emma J, Boyland, Clare L, Lawton, John E, Blundell, Joanne A, Harrold   +4 more
openaire   +2 more sources

Studies on fenfluramhe as an anti-obesity agent

Current Medical Research and Opinion, 1979
SummaryThe results of three studies on the use of fenfluramine in patients with refractory obesity are reviewed. The mean weight loss achieved on continuous therapy compared favourably with that recorded in other studies in similar patients receiving other anorectic agents. It was evident, however, that although all patients on fenfluramine lost weight
P. G. Preston, M. J. Ford, J. F. Munro
openaire   +1 more source