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Adipogenesis [PDF]

Cold Spring Harbor Perspectives in Biology, 2012
Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue development and function, which can be regulated by the endocrine actions of various peptide and steroid hormones.
Kelesha, Sarjeant, Jacqueline M, Stephens   +1 more
core   +5 more sources

Biphasic effects of FGF2 on adipogenesis. [PDF]

PLoS ONE, 2015
Although stem cells from mice deficient of FGF2 have been reported to display enhanced capacity for adipogenesis, the literature using in vitro cell culture system has so far reported conflicting results on the role of FGF2 in adipogenesis.
Sooho Kim, Chihoon Ahn, Naeun Bong, Senyon Choe, Dong Kun Lee   +4 more
doaj   +2 more sources

Weighing in on Adipogenesis [PDF]

Frontiers in Physiology, 2022
Obesity is a growing health concern worldwide because of its contribution to metabolic syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white adipose tissue (WAT) expands through two mechanisms: increase in adipocyte
Elizabeth R. Nunn, Abhijit B. Shinde, Elma Zaganjor   +2 more
doaj   +3 more sources

High Fructose Intake and Adipogenesis [PDF]

International Journal of Molecular Sciences, 2019
In modern societies, high fructose intake from sugar-sweetened beverages has contributed to obesity development. In the diet, sucrose and high fructose corn syrup are the main sources of fructose and can be metabolized in the intestine and transported into the systemic circulation.
Adrián Hernández-Díazcouder, Rodrigo Romero-Nava, Roxana Carbó, L. Gabriela Sánchez-Lozada, Fausto Sánchez-Muñoz   +4 more
openaire   +3 more sources

Pivotal contribution of super-enhancer-driven KLF6 expression to the adipogenesis of human adipose-derived stem cells [PDF]

Inflammation and Regeneration
Background Super-enhancers (SEs), characterized by dense clusters of enhancer elements enriched with transcriptional activator binding sites, are involved in cell differentiation. However, little is known about SE-mediated regulation of adipogenic genes.
Mai-Phuong Nguyen, Kaoru Yamagata, Anh Phuong Nguyen, Tong Zhang, Hidenori Sakai, Uyen Thi Ngo, Yu Shan, Takashi Otsuka, Ngo Thi Dieu Huong, Takafumi Aritomi, Meng Yuan, Shigeaki Kato, Yoshiya Tanaka, Shingo Nakayamada   +13 more
doaj   +2 more sources

Transcriptional Regulation of Adipogenesis

Comprehensive Physiology, 2017
ABSTRACT Adipocytes are the defining cell type of adipose tissue. Once considered a passive participant in energy storage, adipose tissue is now recognized as a dynamic organ that contributes to several important physiological processes, such as lipid metabolism, systemic energy homeostasis, and whole‐body insulin
Paula, Mota de Sá, Allison J, Richard, Hardy, Hang, Jacqueline M, Stephens   +3 more
openaire   +3 more sources

Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation

Molecules, 2022
Excessive storage of lipids in visceral or ectopic sites stimulates adipokine production, which attracts macrophages. This process determines the pro- and anti-inflammatory response regulation in adipose tissue during obesity-associated systemic ...
Pandurangan Subash-Babu, Hussah Mohammed Alowaidh, Laila Naif Al-Harbi, Ghalia Shamlan, Amal A. Aloud, Sahar Abdulaziz AlSedairy, Ali Abdullah Alshatwi   +6 more
doaj   +1 more source

Luteolin-7-O-rutinoside Protects RIN-5F Cells from High-Glucose-Induced Toxicity, Improves Glucose Homeostasis in L6 Myotubes, and Prevents Onset of Type 2 Diabetes

Metabolites, 2023
Luteolin-7-O-rutinoside (lut-7-O-rutin), a flavonoid commonly present in Mentha longifolia L. and Olea europaea L. leaves has been used as a flavoring agent with some biological activity.
Pandurangan Subash-Babu, Sahar Abdulaziz AlSedairy, Manal Abdulaziz Binobead, Ali A. Alshatwi   +3 more
doaj   +1 more source

Genistein regulates adipogenesis by blocking the function of adenine nucleotide translocase-2 in the mitochondria [PDF]

, 2022
Genistein exerts antiadipogenic effects, but its target molecules remain unclear. Here, we delineated the molecular mechanism underlying the antiadipogenic effect of genistein.
Ikeda, Takahiro, Mitani, Takakazu, Watanabe, Shun   +2 more
core   +1 more source

Prevalence of using herbs and natural products as a protective measure during the COVID-19 pandemic among the Saudi population: an online cross-sectional survey

Saudi Pharmaceutical Journal, 2021
Considering that no food or supplement has been authorised to prevent COVID-19, individuals continue to search for and consume specific herbs, foods and commercial supplements for this purpose.
Amna Abdullah Alotiby, Laila Naif Al-Harbi   +1 more
doaj   +1 more source