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Weighing in on Adipogenesis [PDF]

Frontiers in Physiology, 2022
Obesity is a growing health concern worldwide because of its contribution to metabolic syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white adipose tissue (WAT) expands through two mechanisms: increase in adipocyte
Elizabeth R. Nunn, Abhijit B. Shinde, Elma Zaganjor   +2 more
doaj   +3 more sources

Adipogenesis [PDF]

Cold Spring Harbor Perspectives in Biology, 2012
Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue development and function, which can be regulated by the endocrine actions of various peptide and steroid hormones.
Kelesha, Sarjeant, Jacqueline M, Stephens   +1 more
openaire   +3 more sources

Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation

Molecules, 2022
Excessive storage of lipids in visceral or ectopic sites stimulates adipokine production, which attracts macrophages. This process determines the pro- and anti-inflammatory response regulation in adipose tissue during obesity-associated systemic ...
Pandurangan Subash-Babu, Hussah Mohammed Alowaidh, Laila Naif Al-Harbi, Ghalia Shamlan, Amal A. Aloud, Sahar Abdulaziz AlSedairy, Ali Abdullah Alshatwi   +6 more
doaj   +1 more source

Luteolin-7-O-rutinoside Protects RIN-5F Cells from High-Glucose-Induced Toxicity, Improves Glucose Homeostasis in L6 Myotubes, and Prevents Onset of Type 2 Diabetes

Metabolites, 2023
Luteolin-7-O-rutinoside (lut-7-O-rutin), a flavonoid commonly present in Mentha longifolia L. and Olea europaea L. leaves has been used as a flavoring agent with some biological activity.
Pandurangan Subash-Babu, Sahar Abdulaziz AlSedairy, Manal Abdulaziz Binobead, Ali A. Alshatwi   +3 more
doaj   +1 more source

Prevalence of using herbs and natural products as a protective measure during the COVID-19 pandemic among the Saudi population: an online cross-sectional survey

Saudi Pharmaceutical Journal, 2021
Considering that no food or supplement has been authorised to prevent COVID-19, individuals continue to search for and consume specific herbs, foods and commercial supplements for this purpose.
Amna Abdullah Alotiby, Laila Naif Al-Harbi   +1 more
doaj   +1 more source

Regulating Adipogenesis [PDF]

Journal of Biological Chemistry, 1997
Udgivelsesdato: 1997-Feb ...
Mandrup, S; id_orcid 0000-0002-0961-5787, Lane, M D   +1 more
openaire   +2 more sources

A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells

Adipocyte, 2022
Obesity has become a serious global public health problem; a deeper understanding of systemic change of chromatin accessibility during human adipogenesis contributes to conquering obesity and its related diseases.
Sen Li, Xiaolin Zong, Liheng Zhang, Luya Li, Jianxin Wu   +4 more
doaj   +1 more source

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

Scientific Reports, 2021
Cancer-associated adipocytes are known to cause inflammation; however, the role of adipogenesis, the formation of adipocytes, in breast cancer is unclear.
Masanori Oshi, Yoshihisa Tokumaru, Fernando A. Angarita, Lan Lee, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe   +7 more
doaj   +1 more source

Adipogenesis at a glance [PDF]

Journal of Cell Science, 2011
The formation of adipocytes from precursor stem cells involves a complex and highly orchestrated programme of gene expression. Our understanding of the basic network of transcription factors that regulates adipogenesis has remained remarkably unchanged in recent years.
Christopher E, Lowe, Stephen, O'Rahilly, Justin J, Rochford   +2 more
openaire   +3 more sources

Beneficial Fatty Acid Ratio of Salvia hispanica L. (Chia Seed) Potentially Inhibits Adipocyte Hypertrophy, and Decreases Adipokines Expression and Inflammation in Macrophage

Foods, 2020
The present study aimed to determine the role of Salvia hispanica L., (chia seed) fatty acid content in adipocyte lipid accumulation and human macrophage immunoregulatory potential.
Subash-Babu Pandurangan, Salah A. Al-Maiman, Laila Naif Al-Harbi, Ali A. Alshatwi   +3 more
doaj   +1 more source