Results 41 to 50 of about 94,652 (323)
Involvement of geranylgeranylation of Rho and Rac GTPases in adipogenic and RANKL expression, which was inhibited by simvastatin [PDF]
, 2013 Simvastatin suppresses myoblast differentiation via inhibition of Rac GTPase, which is involved in the mevalonic acid pathway that produces cholesterol.
Ohara-Nemoto, Y. +7 more
core +1 more source
[Adipogenesis and osteoporosis].
Revista medica de Chile, 2009 5
Pablo Rodriguez, Juan +4 more
openaire +4 more sources
Molecular Mechanisms of Adipogenesis: The Anti-adipogenic Role of AMP-Activated Protein Kinase
Frontiers in Molecular Biosciences, 2020 Obesity is now a widespread disorder, and its prevalence has become a critical concern worldwide, due to its association with common co-morbidities like cancer, cardiovascular diseases and diabetes.
B. Ahmad +3 more
semanticscholar +1 more source
Dexamethasone-induced selenoprotein S degradation is required for adipogenesis
Journal of Lipid Research, 2013 Although adipogenesis is associated with induction of endoplasmic reticulum (ER) stress, the role of selenoprotein S (SEPS1), an ER resident selenoprotein known to regulate ER stress and ER-associated protein degradation, is unknown.
Choon Young Kim, Kee-Hong Kim
doaj +1 more source
Contribution of adipogenesis to healthy adipose tissue expansion in obesity.
Journal of Clinical Investigation, 2019 The manner in which white adipose tissue (WAT) expands and remodels directly impacts the risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT is associated with increased risk for insulin resistance, whereas ...
Lavanya Vishvanath, Rana K. Gupta
semanticscholar +1 more source
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis
Advancement of science, 2021 Obesity and type 2 diabetes are strongly associated with adipose tissue dysfunction and impaired adipogenesis. Understanding the molecular underpinnings that control adipogenesis is thus of fundamental importance for the development of novel therapeutics
Joanne X. Shen +13 more
semanticscholar +1 more source
Contact with existing adipose tissue is inductive for adipogenesis in matrigel [PDF]
, 2006 The effect of adipose tissue on inductive adipogenesis within Matrigel (BD Biosciences) was assessed by using a murine chamber model containing a vascular pedicle.
Thompson, Erik W. +12 more
core +1 more source
The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
Adipocyte, 2020 We discovered a unique expression pattern of two histone methyltransferases Suv39h1 and Suv39h2 during 3T3-L1 adipogenesis, both of which preferentially catalyse the formation of H3K9 dimethylation (H3K9me2) and further H3K9 trimethylation (H3K9me3), a ...
Jia Jing +7 more
doaj +1 more source
European Journal of Cell Biology, 2013 Adipocytes are the main constituent of adipose tissue and are considered to be a corner stone in the homeostatic control of whole body metabolism. Their primary function is to control energy balance by storing triacylglycerol in periods of energy excess and mobilizing it during energy deprivation.
Aus Tariq, Ali +3 more
openaire +2 more sources
Adipogenesis and WNT signalling [PDF]
Trends in Endocrinology & Metabolism, 2009 An inability of adipose tissue to expand consequent to exhausted capacity to recruit new adipocytes might underlie the association between obesity and insulin resistance. Adipocytes arise from mesenchymal precursors whose commitment and differentiation along the adipocytic lineage is tightly regulated.
Christodoulides, C +3 more
openaire +2 more sources