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The Effects of Coffee Extract on Adipogenesis [PDF]
, 2021 The prevalence of obesity in the United States has increased from 30.5% in 1999 to 42.4% in 2018. Fat cells are created through a process called adipogenesis; in adipogenesis, a preadipocyte, which is an undifferentiated fibroblast, is differentiated ...
Carper, Jaden
core
Inhibition of Adipogenesis by Ghrelin [PDF]
Molecular Biology of the Cell, 2004 Ghrelin, a novel gastric hormone, regulates food intake and energy metabolism via central mechanisms. The peripheral effect of ghrelin on adiposity is poorly understood. We established a stable 3T3-L1 cell line expressing ghrelin to study the direct effect of ghrelin on adipogenesis.
Weizhen, Zhang +6 more
openaire +2 more sources
Advanced Science, 2020 Obesity is a critical risk factor causing the development of metabolic diseases and cancers. Its increasing prevalence worldwide has aroused great concerns of the researchers on adipose development and metabolic function.
Tongxing Song +3 more
doaj +1 more source
Serum amyloid A3 deficiency impairs in vitro and in vivo adipocyte differentiation
Adipocyte, 2021 Obesity, caused by an excess adipose tissue, is one of the biggest health-threats of the 21st century. Adipose tissue expansion occurs through two processes: (i) hypertrophy, and (ii) hyperplasia, the formation of new adipocytes, also termed adipogenesis.
Ellen Vercalsteren +5 more
doaj +1 more source
SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion
Cell Reports, 2017 Preadipocytes initiate differentiation into adipocytes through a cascade of events. Mitotic clonal expansion, as one of the earliest events, is essential for adipogenesis.
Qiang Chen +7 more
doaj +1 more source
Mouse Embryonic Fibroblast Adipogenic Potential: A Comprehensive Transcriptome Analysis
Adipocyte, 2021 Our understanding of adipose tissue has progressed from an inert tissue for energy storage to be one of the largest endocrine organs regulating metabolic homoeostasis through its ability to synthesize and release various adipokines that regulate a myriad
Mohamed Al-Sayegh +6 more
doaj +1 more source
POU2AF1 promotes MSCs adipogenesis by inhibiting HDAC1 expression
Adipocyte, 2021 Excessive production of visceral adipose is a major risk factor of many diseases. Inhibiting the adipogenesis of mesenchymal stem cells (MSCs) will be an efficient way to block adipose production. We illuminated POU class 2 homeobox associating factor 1 (
Yaqing Wang +8 more
doaj +1 more source
Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Nature Communications, 2020 White adipose tissue (WAT) expansion in obesity occurs through enlargement of preexisting adipocytes (hypertrophy) and through formation of new adipocytes (adipogenesis).
Sheng-Peng Wang +16 more
semanticscholar +1 more source
mRNA m5C controls adipogenesis by promoting CDKN1A mRNA export and translation
RNA Biology, 2021 5-Methylcytosine (m5C) is a type of RNA modification that exists in tRNAs and rRNAs and was recently found in mRNA. Although mRNA m5C modification has been reported to regulate diverse biological process, its function in adipogenesis remains unknown ...
You-Hua Liu +12 more
semanticscholar +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source