Results 61 to 70 of about 94,652 (323)

Distinct adipose progenitor cells emerging with age drive active adipogenesis

Science
Starting from middle age, adults often suffer from visceral adiposity and associated adverse metabolic disorders. Lineage tracing in mice revealed that adipose progenitor cells (APCs) in visceral fat undergo extensive adipogenesis during middle age. Thus,
Guan Wang, Gaoyan Li, Anying Song, Yutian Zhao, Jiayu Yu, Yifan Wang, W. Dai, Martha Salas, H. Qin, Leonard Medrano, Joan Dow, Aimin Li, Brian Armstrong, Patrick T. Fueger, Hua Yu, Yi Zhu, Mengle Shao, Xi-Wei Wu, Lei Jiang, Judith Campisi, Xia Yang, Qiong A. Wang   +21 more
semanticscholar   +1 more source

Maternal obesity during pregnancy and lactation influences offspring obesogenic adipogenesis but not developmental adipogenesis in mice [PDF]

, 2019
Obesity is an escalating health crisis of pandemic proportions and by all accounts it has yet to reach its peak. Growing evidence suggests that obesity may have its origins in utero.
Sellayah, Dyan, Thomas, Hugh, Stuart A. Lanham, Lanham, Stuart A., Dyan Sellayah, Hugh Thomas, Felino R. Cagampang, Cagampang, Felino R.   +7 more
core   +1 more source

RACK1 is required for adipogenesis [PDF]

American Journal of Physiology-Cell Physiology, 2016
Adipose tissue plays a critical role in metabolic diseases and the maintenance of energy homeostasis. RACK1 has been identified as an adaptor protein involved in multiple intracellular signal transduction pathways and diseases. However, whether it regulates adipogenesis remains unknown.
Qinghua Kong, Lan Gao, Yanfen Niu, Pianchou Gongpan, Yuhui Xu, Yan Li, Wenyong Xiong   +6 more
openaire   +2 more sources

Non-Coding RNAs and Adipogenesis

, 2023
Adipogenesis is regarded as an intricate network in which multiple transcription factors and signal pathways are involved. Recently, big efforts have focused on understanding the epigenetic mechanisms and their involvement in the regulation of adipocyte ...
Bizhi Huang, Wenxiu Ru, Jianyong Liu, Wujun Liu, Hong Chen, Sihuan Zhang   +5 more
core   +1 more source

A chromatin perspective of adipogenesis [PDF]

Organogenesis, 2010
The transcriptional cascade governing adipogenesis has been thoroughly examined throughout the years. Transcription factors PPARγ and C/EBPα are universally recognized as the master regulators of adipocyte differentiation and together they direct the establishment of the gene expression pattern of mature adipose cells.
Melina M, Musri, Ramon, Gomis, Marcelina, Párrizas   +2 more
openaire   +2 more sources

The Marine Factor 3,5-Dihydroxy-4-methoxybenzyl Alcohol Represses Adipogenesis in Mouse 3T3-L1 Adipocytes In Vitro: Regulating Diverse Signaling Pathways

Nutraceuticals, 2023
The augmentation of adipocytes in the adipose tissues brings disordered pathophysiological conditions, including type 2 diabetes, hyperlipidemia, hypertension, cardiovascular disease, and cancer.
Masayoshi Yamaguchi, Kenji Yoshiike, Hideaki Watanabe, Mitsugu Watanabe   +3 more
doaj   +1 more source

Adipogenesis, Osteogenesis, and Chondrogenesis of Human Mesenchymal Stem/Stromal Cells: A Comparative Transcriptome Approach

Frontiers in Cell and Developmental Biology, 2020
Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal cells (MSC) are complex and highly regulated processes. Over the years, several studies have focused on understanding the mechanisms involved in the MSC commitment to the ...
A. Robert, B. Marcon, B. Dallagiovanna, P. Shigunov   +3 more
semanticscholar   +1 more source

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity

, 2009
We previously described a putative role for inosine monophosphate dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, in lipid accumulation.
Hutley, Louise J., Whitehead, Jonathan P., Connor, Tim, Segal, David, Prins, Johannes B., Walder, Ken, Molero, Juan Carlos, Wanyonyi, Stephen, Reizes, Ofer, de Vries, Melissa, Newell, Felicity S., Su, Hua, Gunter, Jennifer H.   +12 more
core   +1 more source

An investigation of the early molecular regulation of adipogenesis in human mesenchymal stem cells. [PDF]

, 2006
Human bone marrow-derived mesenchymal stem cells (hMSCs) can differentiate in vitro into various lineages including adipocytes, osteoblasts, and chondrocytes.
Westwood, Claire, Westwood, C.
core  

Zymosan-induced inflammation stimulates neo-adipogenesis

, 2008
Objective: To investigate the potential of inflammation to induce new adipose tissue formation in the in vivo environment.\ud \ud Methods and results: Using an established model of in vivo adipogenesis, a silicone chamber containing a Matrigel and ...
G P L Thomas, A J Penington, Thompson, Erik W., W A Morrison, McCombe, D., Penington, A. J., Abberton, K. M., Hemmrich, Karsten, Thompson, E. W., Thomas, G. P. L., Morrison, W. A., D McCombe, Abberton, Keren M., K M Abberton, Hemmrich, K., E W Thompson, K Hemmrich   +16 more
core   +1 more source