Results 21 to 30 of about 94,652 (323)

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port-Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways. [PDF]

Adv Sci (Weinh)
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Chen H, Sun B, Qiu Y, Hua C, Lin X, Gao W.   +5 more
europepmc   +2 more sources

Ocimum basilicum L. Methanol Extract Enhances Mitochondrial Efficiency and Decreases Adipokine Levels in Maturing Adipocytes Which Regulate Macrophage Systemic Inflammation

Molecules, 2022
Excessive storage of lipids in visceral or ectopic sites stimulates adipokine production, which attracts macrophages. This process determines the pro- and anti-inflammatory response regulation in adipose tissue during obesity-associated systemic ...
Pandurangan Subash-Babu, Hussah Mohammed Alowaidh, Laila Naif Al-Harbi, Ghalia Shamlan, Amal A. Aloud, Sahar Abdulaziz AlSedairy, Ali Abdullah Alshatwi   +6 more
doaj   +1 more source

Luteolin-7-O-rutinoside Protects RIN-5F Cells from High-Glucose-Induced Toxicity, Improves Glucose Homeostasis in L6 Myotubes, and Prevents Onset of Type 2 Diabetes

Metabolites, 2023
Luteolin-7-O-rutinoside (lut-7-O-rutin), a flavonoid commonly present in Mentha longifolia L. and Olea europaea L. leaves has been used as a flavoring agent with some biological activity.
Pandurangan Subash-Babu, Sahar Abdulaziz AlSedairy, Manal Abdulaziz Binobead, Ali A. Alshatwi   +3 more
doaj   +1 more source

Genistein regulates adipogenesis by blocking the function of adenine nucleotide translocase-2 in the mitochondria [PDF]

, 2022
Genistein exerts antiadipogenic effects, but its target molecules remain unclear. Here, we delineated the molecular mechanism underlying the antiadipogenic effect of genistein.
Ikeda, Takahiro, Mitani, Takakazu, Watanabe, Shun   +2 more
core   +1 more source

Prevalence of using herbs and natural products as a protective measure during the COVID-19 pandemic among the Saudi population: an online cross-sectional survey

Saudi Pharmaceutical Journal, 2021
Considering that no food or supplement has been authorised to prevent COVID-19, individuals continue to search for and consume specific herbs, foods and commercial supplements for this purpose.
Amna Abdullah Alotiby, Laila Naif Al-Harbi   +1 more
doaj   +1 more source

Regulating Adipogenesis [PDF]

Journal of Biological Chemistry, 1997
Udgivelsesdato: 1997-Feb ...
Mandrup, S; id_orcid 0000-0002-0961-5787, Lane, M D   +1 more
openaire   +2 more sources

Role of Inflammatory Cytokines, Growth Factors and Adipokines in Adipogenesis and Insulin Resistance

Inflammation, 2021
Obesity, manifested by increased adiposity, represents a main cause of morbidity in the developed countries, causing increased risk of insulin resistance and type 2 diabetes mellitus. Recruitment of macrophages and activation of innate immunity represent
Layla Al-mansoori, Hend Al-Jaber, Mohammad Shoaib Prince, Mohamed A. Elrayess   +3 more
semanticscholar   +1 more source

A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells

Adipocyte, 2022
Obesity has become a serious global public health problem; a deeper understanding of systemic change of chromatin accessibility during human adipogenesis contributes to conquering obesity and its related diseases.
Sen Li, Xiaolin Zong, Liheng Zhang, Luya Li, Jianxin Wu   +4 more
doaj   +1 more source

Adipogenesis as a Potential Anti-Obesity Target: A Review of Pharmacological Treatment and Natural Products

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2021
Obesity is recognized as a severe threat to overall human health and is associated with type 2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases.
J. Jakab, B. Miškić, Š. Mikšić, B. Juranić, V. Ćosić, Dragan Schwarz, A. Včev   +6 more
semanticscholar   +1 more source

Beneficial Fatty Acid Ratio of Salvia hispanica L. (Chia Seed) Potentially Inhibits Adipocyte Hypertrophy, and Decreases Adipokines Expression and Inflammation in Macrophage

Foods, 2020
The present study aimed to determine the role of Salvia hispanica L., (chia seed) fatty acid content in adipocyte lipid accumulation and human macrophage immunoregulatory potential.
Subash-Babu Pandurangan, Salah A. Al-Maiman, Laila Naif Al-Harbi, Ali A. Alshatwi   +3 more
doaj   +1 more source