Results 21 to 30 of about 4,022 (213)
A chromatin perspective of adipogenesis [PDF]
Organogenesis, 2010 The transcriptional cascade governing adipogenesis has been thoroughly examined throughout the years. Transcription factors PPARγ and C/EBPα are universally recognized as the master regulators of adipocyte differentiation and together they direct the establishment of the gene expression pattern of mature adipose cells.
Melina M, Musri +2 more
openaire +2 more sources
The histone methyltransferase Suv39h regulates 3T3-L1 adipogenesis
Adipocyte, 2020 We discovered a unique expression pattern of two histone methyltransferases Suv39h1 and Suv39h2 during 3T3-L1 adipogenesis, both of which preferentially catalyse the formation of H3K9 dimethylation (H3K9me2) and further H3K9 trimethylation (H3K9me3), a ...
Jia Jing +7 more
doaj +1 more source
Redox Biology, 2020 Adipogenesis is a fundamental process of white adipose tissue function, supporting lipid storage and release, while avoiding its spillover and ectopic accumulation in tissues and organs.
Raquel Fernando +10 more
doaj +1 more source
[Adipogenesis and osteoporosis].
Revista medica de Chile, 2009 5
Pablo Rodriguez, Juan +4 more
openaire +4 more sources
Advanced Science, 2020 Obesity is a critical risk factor causing the development of metabolic diseases and cancers. Its increasing prevalence worldwide has aroused great concerns of the researchers on adipose development and metabolic function.
Tongxing Song +3 more
doaj +1 more source
Serum amyloid A3 deficiency impairs in vitro and in vivo adipocyte differentiation
Adipocyte, 2021 Obesity, caused by an excess adipose tissue, is one of the biggest health-threats of the 21st century. Adipose tissue expansion occurs through two processes: (i) hypertrophy, and (ii) hyperplasia, the formation of new adipocytes, also termed adipogenesis.
Ellen Vercalsteren +5 more
doaj +1 more source
SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion
Cell Reports, 2017 Preadipocytes initiate differentiation into adipocytes through a cascade of events. Mitotic clonal expansion, as one of the earliest events, is essential for adipogenesis.
Qiang Chen +7 more
doaj +1 more source
Mouse Embryonic Fibroblast Adipogenic Potential: A Comprehensive Transcriptome Analysis
Adipocyte, 2021 Our understanding of adipose tissue has progressed from an inert tissue for energy storage to be one of the largest endocrine organs regulating metabolic homoeostasis through its ability to synthesize and release various adipokines that regulate a myriad
Mohamed Al-Sayegh +6 more
doaj +1 more source
RACK1 is required for adipogenesis [PDF]
American Journal of Physiology-Cell Physiology, 2016 Adipose tissue plays a critical role in metabolic diseases and the maintenance of energy homeostasis. RACK1 has been identified as an adaptor protein involved in multiple intracellular signal transduction pathways and diseases. However, whether it regulates adipogenesis remains unknown.
Qinghua Kong +6 more
openaire +2 more sources
POU2AF1 promotes MSCs adipogenesis by inhibiting HDAC1 expression
Adipocyte, 2021 Excessive production of visceral adipose is a major risk factor of many diseases. Inhibiting the adipogenesis of mesenchymal stem cells (MSCs) will be an efficient way to block adipose production. We illuminated POU class 2 homeobox associating factor 1 (
Yaqing Wang +8 more
doaj +1 more source