Results 11 to 20 of about 94,652 (323)
Cold Spring Harbor Perspectives in Biology, 2020 Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue development and function, which can be regulated by the endocrine ...
K. Sarjeant, J. Stephens
semanticscholar +5 more sources
A spatiotemporal proteomic map of human adipogenesis
bioRxiv, 2023 White adipocytes function as the major energy reservoir in humans by storing substantial amounts of triglycerides and their dysfunction is associated with metabolic disorders. However, the mechanisms underlying cellular specialization during adipogenesis
Felix Klingelhuber +14 more
semanticscholar +2 more sources
Weighing in on Adipogenesis [PDF]
Frontiers in Physiology, 2022 Obesity is a growing health concern worldwide because of its contribution to metabolic syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white adipose tissue (WAT) expands through two mechanisms: increase in adipocyte
Elizabeth R. Nunn +2 more
doaj +3 more sources
Biphasic effects of FGF2 on adipogenesis. [PDF]
PLoS ONE, 2015 Although stem cells from mice deficient of FGF2 have been reported to display enhanced capacity for adipogenesis, the literature using in vitro cell culture system has so far reported conflicting results on the role of FGF2 in adipogenesis.
Sooho Kim +4 more
doaj +2 more sources
Transcriptional regulation of adipogenesis. [PDF]
Genes & Development, 2000 The past twenty years have seen great strides in our understanding of the molecular regulation of differentiation for a whole host of specific cell types. The development of muscle, bone, pituitary, and several hematopoeitic lineages have all been probed
E. Rosen +3 more
semanticscholar +5 more sources
Redox Biology, 2020 Adipogenesis is a fundamental process of white adipose tissue function, supporting lipid storage and release, while avoiding its spillover and ectopic accumulation in tissues and organs.
José Pedro Castro +2 more
exaly +3 more sources
Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules
International Journal of Molecular Sciences, 2016 Adipogenesis is the process by which precursor stem cells differentiate into lipid laden adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene expression program.
Alemu Regassa +2 more
exaly +2 more sources
Modeling Adipogenesis: Current and Future Perspective [PDF]
Cells, 2020 Adipose tissue is contemplated as a dynamic organ that plays key roles in the human body. Adipogenesis is the process by which adipocytes develop from adipose-derived stem cells to form the adipose tissue.
H. Bahmad +6 more
semanticscholar +2 more sources
Harnessing adipogenesis to prevent obesity [PDF]
Adipocyte, 2019 Obesity and associated metabolic complications, including diabetes, cardiovascular and hepatic diseases, and certain types of cancers, create a major socioeconomic burden.
Nida Haider, Louise Larose
doaj +3 more sources
Development of methods for the in-vitro assessment of the adipogenesis and immunogenicity of human multipotent mesenchymal stromal cells [PDF]
, 2011 Adult mesenchymal stromal cells (MSCs) have enormous potential in tissue engineering and regenerative medicine applications. MSC have also been reported to be immune-privileged.
Aldridge, Andrew Robert
core +6 more sources