Results 11 to 20 of about 56,993 (237)
Weighing in on Adipogenesis [PDF]
Frontiers in Physiology, 2022 Obesity is a growing health concern worldwide because of its contribution to metabolic syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white adipose tissue (WAT) expands through two mechanisms: increase in adipocyte
Elizabeth R. Nunn +2 more
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Harnessing adipogenesis to prevent obesity [PDF]
Adipocyte, 2019 Obesity and associated metabolic complications, including diabetes, cardiovascular and hepatic diseases, and certain types of cancers, create a major socioeconomic burden.
Nida Haider, Louise Larose
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Cold Spring Harbor Perspectives in Biology, 2012 Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue development and function, which can be regulated by the endocrine actions of various peptide and steroid hormones.
Kelesha, Sarjeant +1 more
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Journal of Biological Chemistry, 1997 Udgivelsesdato: 1997-Feb ...
Mandrup, S, Lane, M D
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Adipocyte differentiation between obese and lean conditions depends on changes in miRNA expression
Scientific Reports, 2022 Adipogenesis is the process by which precursor cells, preadipocytes (preACs), differentiate into adipocytes (ACs). Here, we investigated differentially expressed miRNAs (DEMs) between the two conditions to understand the regulatory role of miRNAs in ...
Yerim Heo +3 more
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Biphasic effects of FGF2 on adipogenesis. [PDF]
PLoS ONE, 2015 Although stem cells from mice deficient of FGF2 have been reported to display enhanced capacity for adipogenesis, the literature using in vitro cell culture system has so far reported conflicting results on the role of FGF2 in adipogenesis.
Sooho Kim +4 more
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Adipogenesis and WNT signalling [PDF]
Trends in Endocrinology & Metabolism, 2009 An inability of adipose tissue to expand consequent to exhausted capacity to recruit new adipocytes might underlie the association between obesity and insulin resistance. Adipocytes arise from mesenchymal precursors whose commitment and differentiation along the adipocytic lineage is tightly regulated.
Christodoulides, C +3 more
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Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis. [PDF]
PLoS ONE, 2013 BACKGROUND: During mesenchymal stem cell (MSC) conversion into adipocytes, the adipogenic cocktail consisting of insulin, dexamethasone, indomethacin and 3-isobutyl-1-methylxanthine not only induces adipogenic-specific but also genes for non-adipogenic ...
Mujib Ullah +5 more
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Dexamethasone-induced selenoprotein S degradation is required for adipogenesis
Journal of Lipid Research, 2013 Although adipogenesis is associated with induction of endoplasmic reticulum (ER) stress, the role of selenoprotein S (SEPS1), an ER resident selenoprotein known to regulate ER stress and ER-associated protein degradation, is unknown.
Choon Young Kim, Kee-Hong Kim
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Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source