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Regulating Adipogenesis [PDF]

open access: yesJournal of Biological Chemistry, 1997
Udgivelsesdato: 1997-Feb ...
Mandrup, S; id_orcid 0000-0002-0961-5787   +1 more
openaire   +2 more sources

A chromatin accessibility landscape during early adipogenesis of human adipose-derived stem cells

open access: yesAdipocyte, 2022
Obesity has become a serious global public health problem; a deeper understanding of systemic change of chromatin accessibility during human adipogenesis contributes to conquering obesity and its related diseases.
Sen Li   +4 more
doaj   +1 more source

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

open access: yesScientific Reports, 2021
Cancer-associated adipocytes are known to cause inflammation; however, the role of adipogenesis, the formation of adipocytes, in breast cancer is unclear.
Masanori Oshi   +7 more
doaj   +1 more source

Adipogenesis at a glance [PDF]

open access: yesJournal of Cell Science, 2011
The formation of adipocytes from precursor stem cells involves a complex and highly orchestrated programme of gene expression. Our understanding of the basic network of transcription factors that regulates adipogenesis has remained remarkably unchanged in recent years.
Christopher E, Lowe   +2 more
openaire   +3 more sources

Beneficial Fatty Acid Ratio of Salvia hispanica L. (Chia Seed) Potentially Inhibits Adipocyte Hypertrophy, and Decreases Adipokines Expression and Inflammation in Macrophage

open access: yesFoods, 2020
The present study aimed to determine the role of Salvia hispanica L., (chia seed) fatty acid content in adipocyte lipid accumulation and human macrophage immunoregulatory potential.
Subash-Babu Pandurangan   +3 more
doaj   +1 more source

METTL3 mediates bone marrow mesenchymal stem cell adipogenesis to promote chemoresistance in acute myeloid leukaemia

open access: yesFEBS Open Bio, 2021
Adipogenesis of bone marrow mesenchymal stem cells (MSCs) promotes chemoresistance of acute myeloid leukaemia (AML) cells. MSCs from AML patients (AML‐MSCs) display enhanced adipogenesis compared with bone marrow MSCs from healthy donors.
Zhi‐peng Pan   +6 more
doaj   +1 more source

RNA-seq analysis reveals the critical role of the novel lncRNA BIANCR in intramuscular adipogenesis through the ERK1/2 signaling pathway

open access: yesJournal of Animal Science and Biotechnology, 2023
Background Long non-coding RNAs (lncRNAs) regulate numerous biological processes, including adipogenesis. Research on adipogenesis will assist in the treatment of human metabolic diseases and improve meat quality in livestock, such as the content of ...
Xinhao Ma   +8 more
doaj   +1 more source

Regulatory network of metformin on adipogenesis determined by combining high-throughput sequencing and GEO database

open access: yesAdipocyte, 2022
Adipose differentiation and excessive lipid accumulation are the important characteristics of obesity. Metformin, as a classic hypoglycaemic drug, has been proved to reduce body weight in type 2 diabetes, the specific mechanism has not been completely ...
Zhicong Zhao   +12 more
doaj   +1 more source

Adipocyte differentiation between obese and lean conditions depends on changes in miRNA expression

open access: yesScientific Reports, 2022
Adipogenesis is the process by which precursor cells, preadipocytes (preACs), differentiate into adipocytes (ACs). Here, we investigated differentially expressed miRNAs (DEMs) between the two conditions to understand the regulatory role of miRNAs in ...
Yerim Heo   +3 more
doaj   +1 more source

Bisecting GlcNAc Protein N-Glycosylation Is Characteristic of Human Adipogenesis

open access: yes, 2021
Human adipose tissue contains a major source of adipose-derived stem cells (ADSCs) that have the ability to differentiate into various cell types: in vitro, ADSCs can differentiate into mesenchymal lineages including adipocytes, while in vivo, ADSCs ...
Wongtrakul-Kish, Katherine   +2 more
core   +1 more source

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