Results 151 to 160 of about 17,829 (260)
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Transnational Politics of Anti-Gender Mobilizations
Katja Kahlina +2 more
doaj +1 more source
You aren't going to like what comes after America: Europe and global health after 2025. [PDF]
Greer SL.
europepmc +1 more source
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu +4 more
wiley +1 more source
How social and political participation in later life divergently impact on perceived health of older adults: a case study in Central Italy. [PDF]
Cantore M, Santini S, Socci M.
europepmc +1 more source
An electro‐templating strategy directs the relaxation of cholesteric finger loops into discrete concentric rings whose geometry is electrically programmed. The photopolymerized structures retain the topological defect pattern and, upon heating, show reversible, castle‐like surface modulation.
Jacques A. Peixoto +4 more
wiley +1 more source

