Results 101 to 110 of about 2,257,590 (283)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Anti-realism: the manifestation of semantic knowledge
Realistic views are fashionable. In this thesis, Slade defends a view opposed to realism, which Dummett calls "anti-realism". Her defence of anti-realism depends on the assumption that a theory of meaning should explain how speakers understand one ...
Slade, C
core +3 more sources
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
A brief review of realism and anti-realism in science [PDF]
A brief review of realism and anti-realism in science Abstract: This paper delves into the realms of scientific realism and anti-realism, engaging in a comprehensive examination of their philosophical underpinnings.
Euune-lim, Kim
core +3 more sources
, 2009 Abstract The basic question of ontology is ‘What exists?’ The basic question of metaontology is: are there objective answers to the basic question of ontology? Here ontological realists say yes, and ontological anti-realists say no.
openaire +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Hacking Stereoscopic Vision: the Nineteenth-Century Culture of Critical Inquiry in Stereoscope Use
International Journal of Film and Media Arts, 2016 While recent scholarship has emphasised the narratives of immersive realism that surrounded the parlour stereoscope, my aim in this paper is to better understand the counter-currents of nineteenth century stereoscopic culture – the artefacts, practices ...
Rod Bantjes
doaj
“Sculpting from Time”: Attempts at Philosophical Reconstruction of A. Tarkovsky’s Legacy
Галактика медиа: журнал медиа исследованийThe article analyzes the work of film director Andrei Tarkovsky through an appeal to modern scientific versions of the interpretation of his films. The problematic of the study is related to the fact that despite the significant corpus of works devoted ...
Anastasia V. Kucherova
doaj +1 more source