Results 111 to 120 of about 12,098 (310)

The End of the Will to Power: From Aesthetics to Theology

open access: yesEidos. A Journal for Philosophy of Culture
In a critical commentary on the final paragraph of The Will to Power (Der Wille zur Macht, ¶1067 (1885)) it is argued that Nietzsche ironically presupposes the metaphysics, and even the theology, he putatively eschews and repudiates.
Stephen Priest
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Presume It Not: True Causes in the Search for the Basis of Heredity [PDF]

open access: yes, 2017
Kyle Stanford has recently given substance to the problem of unconceived alternatives, which challenges the reliability of inference to the best explanation (IBE) in remote domains of nature.
Novick, Aaron, Scholl, Raphael
core   +1 more source

The Problem of Unobservable A Defense of Van Fraassen’s Distinction between Observable and Unobservable [PDF]

open access: yesMetaphysics, 2015
In constructive empiricism Van Fraassen intends to defend the epistemological distinction between truth and empirical adequacy as well as between cognitive belief and pragmatic acceptance, based on epistemological distinction between observable entities ...
Jahangir Moazzenzade   +1 more
doaj  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Cultivating Critical Thinking Skill In Teaching And Learning And Learning Process [PDF]

open access: yes, 2008
The purpose of this article is to spearhead two objectives namely, to fulfill my assignment and to help our future leaders that are our beloved student to analyze multilogical problem of contemporary in teaching and learning process .
Yahaya, Azizi
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A Correspondence Theory of Objects? On Kant's Notions of Object, Truth, and Actuality [PDF]

open access: yes, 2008
Ernst Cassirer claimed that Kant's notion of actual object presupposes the notion of truth. Therefore, Kant cannot define truth as the correspondence of a judgment with an actual object.
Vanzo, Alberto
core  

Anti-Realism under Mind?

open access: yesDialectica, 1989
Summary Anti-Realism claims that the Classical or Realist conception of truth as verification-transcendent is incoherent. Our grasp of the meanings of statements from any given class is to be assimilated to a grasp of their assertibility or deniability conditions.
openaire   +1 more source

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