Results 41 to 50 of about 1,756 (252)
This article identifies a form of affective bio-politics more intimate, engrained and corporeally enacted than that identified in recent work emphasising the affective qualities of activism and labour.
Healy, Stephen
core +2 more sources
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley +1 more source
Thinking conjuncturally about ideology, housing and English planning [PDF]
This paper explores the value of Stuart Hall’s approach to conjunctural analysis for examining the complex relations between ideology and planning. By “thinking conjuncturally” we explore planning as a site where multiple social, economic and political ...
Inch, Andy, Shepherd, Edward
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A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
Shooting for freedom: what guns teach us about US political culture [PDF]
The right to bear arms is a fundamental tenet of freedom for many Americans. But it is often met with incomprehension in the UK and Europe. Dylan McLean unpicks the origins of America’s gun culture, tracing it back to the militia in Tudor society, and ...
McLean, Dylan
core
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su +10 more
wiley +1 more source
Sex Tourism and the Ethics of Contingent Responsibility [PDF]
Sitting in the garden of the bar Chez Angeline in the perfumed island of Nosy Bé in Madagascarperfumed literally by culture of the Ylang-Ylang flowerI was transfixed by the singing of a raggedy minstrel with a home-made vahila, the Madagascan guitar.
Muecke, S
core
CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou +5 more
wiley +1 more source
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source

