Results 1 to 10 of about 10,431 (136)

Anti‐thymocyte globulin‐mediated immunosenescent alterations of T cells in kidney transplant patients [PDF]

Clinical & Translational Immunology, 2022
Objectives Kidney transplant (KT) is the most effective treatment for end‐stage renal disease. The immunosuppressant anti‐thymocyte globulin (ATG) has been applied for induction therapy to reduce the risk of acute transplant rejection for patients at ...
Ga Hye Lee, Jee Youn Lee, Jiyeon Jang, Yeon Jun Kang, Seung Ah Choi, Hyeon Chang Kim, Sungha Park, Myoung Soo Kim, Won‐Woo Lee   +8 more
doaj   +2 more sources

Evaluation of Current and Novel Dosing Strategies for Anti‐Thymocyte Globulin in Adult Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

CPT: Pharmacometrics & Systems Pharmacology
Anti‐thymocyte globulin (ATG) is a polyclonal antibody used to prevent graft‐versus‐host disease in allogeneic hematopoietic stem cell transplantation.
Elias Biris, Phillip R. Selby, Tahlia R. Meola, Stephanie E. Reuter   +3 more
doaj   +2 more sources

Haploidentical Hematopoietic Stem Cell Transplantation With Anti‐Thymocyte Globulin in the Treatment of Older Adults With Hematological Malignancy [PDF]

eJHaem
Objectives Studies on the efficacy and safety of haploidentical hematopoietic stem cell transplantation (haplo‐SCT) with anti‐thymocyte globulin (ATG) in patients aged ≥ 60 years remain limited.
Xin Kong, Jingjing Han, Yin Liu, Baoquan Song, Xiaowen Tang, Shengli Xue, Miao Miao, Yue Han, Ying Wang, Suning Chen, Aining Sun, Mingming Hu, Jun Chen, Feng Chen, Jian Zhang, Hui‐Ying Qiu, Depei Wu   +16 more
doaj   +2 more sources

Case Report: Successful treatment of steroid- and ruxolitinib-refractory gastrointestinal acute graft-versus-Host disease with anti-thymocyte globulin [PDF]

Frontiers in Immunology
Acute graft-versus-host disease (aGVHD), particularly with gastrointestinal (GI) involvement, remains a life-threatening complication after allogeneic hematopoietic stem cell transplantation (HSCT).
Lulu Zhang, Fan Wu, Huiping Wang, Zhimin Zhai, Lili Tao   +4 more
doaj   +2 more sources

Therapeutic potential of anti-thymocyte globulin in type 1 diabetes: A systematic review. [PDF]

PLoS ONE
BackgroundType 1 diabetes (T1D) is an autoimmune condition characterized by the destruction of insulin-producing beta cells in the pancreas. Anti-Thymocyte Globulin (ATG) has emerged as a promising immunomodulatory therapy aimed at preserving beta-cell ...
Rahul Mittal, Keelin McKenna, Joana R N Lemos, Shreya Juneja, Mannat Mittal, Khemraj Hirani   +5 more
doaj   +2 more sources

Comparison of alemtuzumab, anti-thymocyte globulin, and post-transplant cyclophosphamide for graft-versus-host disease and graft-versus-leukemia in murine models.

PLoS ONE, 2021
Graft-versus-host disease is a major complication after allogeneic hematopoietic stem cell transplantation for hematological malignancies. Immunosuppressive drugs, such as anti-thymocyte globulin, alemtuzumab, and post-transplant cyclophosphamide, have ...
Kiyomi Mashima, Iekuni Oh, Ken Fujiwara, Junko Izawa, Norihito Takayama, Hirofumi Nakano, Yasufumi Kawasaki, Daisuke Minakata, Ryoko Yamasaki, Kaoru Morita, Masahiro Ashizawa, Chihiro Yamamoto, Kaoru Hatano, Kazuya Sato, Ken Ohmine, Shin-Ichiro Fujiwara, Nobuhiko Ohno, Yoshinobu Kanda   +17 more
doaj   +1 more source

Anti-thymocyte globulin in immune-mediated cytopenias: A monocentric experience and literature review [PDF]

British Journal of Haematology
Valeria Visconte, Luca Guarnera, Matteo D'Addona   +2 more
exaly   +2 more sources

Allogeneic peripheral blood stem cell transplantation with anti-thymocyte globulin versus allogeneic bone marrow transplantation without anti-thymocyte globulin

Haematologica, 2020
We compared severe graft-versus-host-disease (GvHD) free and relapse-free survival and other transplantation outcomes of acute myeloid leukemia (AML) patients given bone marrow (BM) without anti-thymocyte globulin (ATG) versus peripheral blood stem cells
Frédéric Baron, Jacques-Emmanue Galimard, Myriam Labopin, Ibrahim Yakoub-Agha, Riitta Niittyvuopio, Nicolaus Kröger, Laimonas Griskevicius, Depei Wu, Edouard Forcade, Carlos Richard, Mahmoud Aljurf, Grzegorz Helbig, Hélène Labussière-Wallet, Mohamad Mohty, Arnon Nagler   +14 more
doaj   +1 more source

Modest dose anti-thymocyte globulin administered intraoperatively is safe and effective in kidney transplantations: a retrospective study [PDF]

PeerJ, 2019
Background Anti-thymocyte globulin (ATG) as induction therapy in renal transplantation is facing the dilemma of reducing the incidence of acute rejection (AR) and delayed graft function (DGF) or increasing risks of infection and malignancy.
Hui-Ying Liu, Yuan-Tso Cheng, Hao Lun Luo, Chiang-Chi Huang, Chien Hsu Chen, Yuan-Chi Shen, Wen-Chin Lee   +6 more
doaj   +2 more sources

Application prospect of low-dose porcine anti-thymocyte globulin in HLA-matched sibling donor transplantation

Hematology, 2023
Objective To investigate the preventive effect of low-dose porcine anti-thymocyte globulin (P-ATG) on graft versus host disease (GVHD) in patients' donors over 40 years old or female donors undergoing HLA-matched sibling donor hematopoietic stem cell ...
Xin Chen, Yueshen Ma, Rongli Zhang, Weihua Zhai, Qiaoling Ma, Aiming Pang, Donglin Yang, Jialin Wei, Yi He, Zhen Song, Sizhou Feng, Mingzhe Han, Erlie Jiang   +12 more
doaj   +1 more source