Results 11 to 20 of about 1,983,235 (163)

Comparison of Basiliximab and Anti‐Thymocyte Globulin as Induction Therapy in Pediatric Heart Transplantation: A Survival Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundBasiliximab and anti‐thymocyte globulin are widely used drugs for induction therapy after pediatric heart transplantation. The aim of this study was to determine whether any differences could be observed between basiliximab and anti‐thymocyte ...
David Ansari, Peter Höglund, Bodil Andersson, Johan Nilsson   +3 more
doaj   +3 more sources

A phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction [PDF]

Haematologica, 2014
Immune dysregulation is a mechanism contributing to ineffective hematopoiesis in a subset of myelodysplastic syndrome patients. We report the first US multicenter non-randomized, phase II trial examining the efficacy of rabbit(r)-anti-thymocyte globulin ...
Rami S. Komrokji, Adam W. Mailloux, Dung-Tsa Chen, Mikkael A. Sekeres, Ronald Paquette, William J. Fulp, Chiharu Sugimori, Jennifer Paleveda-Pena, Jaroslaw P. Maciejewski, Alan F. List, Pearlie K. Epling-Burnette   +10 more
doaj   +2 more sources

Prolonged, low-dose anti-thymocyte globulin, combined with CTLA4-Ig, promotes engraftment in a stringent transplant model. [PDF]

PLoS ONE, 2013
Despite significant nephrotoxicity, calcineurin inhibitors (CNIs) remain the cornerstone of immunosuppression in solid organ transplantation. We, along with others, have reported tolerogenic properties of anti-thymocyte globulin (ATG, Thymoglobulin ...
Francesca D'Addio, Olaf Boenisch, Ciara N Magee, Melissa Y Yeung, Xueli Yuan, Bechara Mfarrej, Andrea Vergani, Mohammed Javeed Ansari, Paolo Fiorina, Nader Najafian   +9 more
doaj   +3 more sources

Anti Thymocyte Globulin-Based Treatment for Acquired Bone Marrow Failure in Adults [PDF]

Cells, 2021
Idiopathic acquired aplastic anemia can be successfully treated with Anti Thymocyte Globulin (ATG)-based immune suppressive therapy and is therefore considered a T cell-mediated auto immune disease.
Jennifer M.-L. Tjon, Saskia M. C. Langemeijer, Constantijn J. M. Halkes   +2 more
doaj   +3 more sources

Anti T-lymphocyte Globulin (Grafalon®) Use during Rabbit Anti-thymocyte Globulin (Thymoglobulin®) Shortage – A Single-center Experience

Indian Journal of Transplantation
Introduction: During a period of local nonavailability of rabbit anti-thymocyte globulin (rATG) in India, anti-T-lymphocyte globulin (ATLG) was utilized in high-risk renal transplantation.
Shailendra Tiwari, Namrata S Rao, Abhilash Chandra, Majibullah Ansari, Sanjeet Kumar Singh   +4 more
doaj   +2 more sources

Anti-thymocyte globulin induces neoangiogenesis and preserves cardiac function after experimental myocardial infarction. [PDF]

PLoS ONE, 2012
RationaleAcute myocardial infarction (AMI) followed by ventricular remodeling is the major cause of congestive heart failure and death in western world countries.ObjectiveOf relevance are reports showing that infusion of apoptotic leucocytes or anti ...
Michael Lichtenauer, Michael Lichtenauer, Michael Mildner, Gregor Werba, Lucian Beer, Konrad Hoetzenecker, Andrea Baumgartner, Matthias Hasun, Stefanie Nickl, Andreas Mitterbauer, Matthias Zimmermann, Mariann Gyöngyösi, Bruno Karl Podesser, Walter Klepetko, Hendrik Jan Ankersmit   +14 more
doaj   +2 more sources

Reversible pulmonary fibrosis after receiving anti-thymocyte globulin and cytomegalovirus infection [PDF]

The Journal of Qazvin University of Medical Sciences, 2015
In the past decade, pulmonary dysfunction has been reported due to treatment with anti-thymocyte globulin (ATG) in patients suffering from rejection of organ transplantation or aplastic anemia.
A. Kiani, B. Bromand, R. Sami
doaj   +1 more source

Anti-thymocyte globulin exposure in patients with diffuse cutaneous systemic sclerosis undergoing autologous haematopoietic stem cell transplantation. [PDF]

J Scleroderma Relat Disord, 2023
Introduction: Autologous haematopoietic stem cell transplantation improves event-free survival and lung function and reduces skin thickening in patients with progressive diffuse cutaneous systemic sclerosis.
Chiu YH, Drijver A, Admiraal R, van Rhenen A, Nierkens S, van Laar JM, Spierings J.   +6 more
europepmc   +2 more sources

Individualised dosing of anti-thymocyte globulin in paediatric unrelated allogeneic haematopoietic stem-cell transplantation (PARACHUTE): a single-arm, phase 2 clinical trial [PDF]

, 2022
Background: Anti-thymocyte globulin, which is used in the conditioning of haematopoietic stem-cell transplantation (HSCT) to prevent graft-versus-host disease (GVHD) and graft failure, has highly variable pharmacokinetics.
van Vliet, Ineke, Lindemans, C.A., Versluijs, A. Birgitta, Zwaan, C. Michel, Boelens, Jaap Jan, A Birgitta Versluijs, Lindemans, Caroline A., Vliet, I. van, Lopez-Yurda, M., Lopez-Yurda, Marta, Marta Lopez-Yurda, Admiraal, R., Rick Admiraal, Stefan Nierkens, Bierings, Marc B., Nierkens, S., Bierings, M.B., Robbert G M Bredius, Bredius, Robbert G.M., Bredius, R.G.M., Marc B Bierings, Nierkens, Stefan, Jiang, Y.L., C Michel Zwaan, Admiraal, Rick, Jaap Jan Boelens, Jiang, Yilin, Ineke van Vliet, Yilin Jiang, Caroline A Lindemans, Zwaan, C.M., Boelens, J.J., Versluijs, A.B.   +32 more
core   +3 more sources

Adverse outcomes according to the dosage of anti-thymocyte globulin.

, 2023
Adverse outcomes according to the dosage of anti-thymocyte globulin.
Dong Hyun Kim (184121), Young Hoon Kim (554681), Joo Hee Jung (4567987), Yu-Mee Wee (14701181), Mi Joung Kim (14701184), Hyunwook Kwon (4091746), Seong Jun Lim (11383763), Duck Jong Han (3998090), Monica Young Choi (14701187), Sung Shin (3401819), Youngmin Ko (3333819)   +10 more
core   +1 more source