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Pharmacological Evaluation of Saccharum Officinarum Linn. as Anti-ulcer Agent
International Journal of Science, Technology & Society, 2018The purpose of the study was to elucidate the antiulcer activity of stem of Saccharum Officinarum (Poaceae) in albino rats against aspirin induced gastric ulcer, ethanol induced gastric ulcer and pylorus ligation induced gastric ulcer models. Groups of rats were fasted overnight, received ranitidine (20 mg/kg) as a standard and plant stem juice extract
Preksha Dwivedi +3 more
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Advanced Materials Research, 2014
A pair of triazole-linked bistetrahydrobenzofuran derivatives were prepared in high yields through Cu (II)-catalyzed click reaction under mild conditions. All of the intermediates and target compounds were characterized by NMR, IR, ESI-MS and elemental analysis. The in vitro H+/K+-ATPase inhibitory effect for the target compounds were also evaluated by
Hu Biao Fang +5 more
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A pair of triazole-linked bistetrahydrobenzofuran derivatives were prepared in high yields through Cu (II)-catalyzed click reaction under mild conditions. All of the intermediates and target compounds were characterized by NMR, IR, ESI-MS and elemental analysis. The in vitro H+/K+-ATPase inhibitory effect for the target compounds were also evaluated by
Hu Biao Fang +5 more
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Journal of Chromatography B: Biomedical Sciences and Applications, 1982
A highly specific and sensitive method for the determination of the anti-ulcer drug geranylgeranylacetone (GGA) in human serum is described. The extract from serum with hexane was saponified with potassium hydroxide and subjected to silica gel column chromatography to remove interfering substances. GGA in the partially purified extract was then reacted
Michiru Tanaka +3 more
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A highly specific and sensitive method for the determination of the anti-ulcer drug geranylgeranylacetone (GGA) in human serum is described. The extract from serum with hexane was saponified with potassium hydroxide and subjected to silica gel column chromatography to remove interfering substances. GGA in the partially purified extract was then reacted
Michiru Tanaka +3 more
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LC determination of the anti-ulcer agent CDRI-85/92 in rat serum
Journal of Pharmaceutical and Biomedical Analysis, 2002CDRI-85/92 is a new potent anti-ulcer compound developed by Central Drug Research Institute, Lucknow (India). This compound is in advanced stage of preclinical trials. A High-performance liquid chromatographic (HPLC) method was developed and validated for the analysis of CDRI-85/92 using rat serum.
Pratima Srivastava, Ram Chandra Gupta
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Surgical Infections, 2019
Background: Peptic ulcer disease (PUD) affects four million people worldwide. Perforated peptic ulcer (PPU) occurs in less than 15% of cases but is associated with significant morbidity and mortality rates.
J. Huston +4 more
semanticscholar +1 more source
Background: Peptic ulcer disease (PUD) affects four million people worldwide. Perforated peptic ulcer (PPU) occurs in less than 15% of cases but is associated with significant morbidity and mortality rates.
J. Huston +4 more
semanticscholar +1 more source
Overview: Recent Developments in Anti-ulcer Agents
Current Opinion on Therapeutic Patents, 1992Istvan Szabadkai, Kalman Harsanyi
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Anti-Ulcer effect of FK 506, immunosuppressive agent, in rats
Journal of Gastroenterology, 1994Toshiyuki Kuwabara +5 more
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