Results 261 to 270 of about 381,827 (331)

Bioanalysis of anti-ulcer agents

Journal of Chromatography B: Biomedical Sciences and Applications, 1990
In reviewing the analytical methods for the analysis of anti-ulcer drugs we observed an increase in the utilization of solid-phase extraction techniques, though the traditional liquid-liquid methods are still predominant. Liquid chromatographic techniques are employed more than gas chromatographic methods which reflects the general trend in ...
K R, Mallikaarjun, H T, Karnes
openaire   +3 more sources

Lung lesions and anti-ulcer agents beneficial effect: Anti-ulcer agents pentadecapeptide BPC 157, ranitidine, omeprazole and atropine ameliorate lung lesion in rats

Journal of Physiology-Paris, 2001
Anti-ulcer agents may likely attenuate lesions outside the gastrointestinal tract, since they had protected gastrectomized rats (a "direct cytoprotective effect"). Therefore, their therapeutic potential in lung/stomach lesions were shown. Rats received an intratracheal (i.t.) HCl instillation [1.5 ml/kg HCl (pH 1.75)] (lung lesion), and an intragastric
Stančić-Rokotov, Dinko, Slobodnjak, Zoran, Aralica, Josip, Aralica, Gorana, Perović, Darko, Starešinić, Mario, Gjurašin, Miroslav, Anić, Tomislav, Zoričić, Ivan, Buljat, Gojko, Prkačin, Ingrid, Sikirić, Predrag, Seiwerth, Sven, Ručman, Rudolf, Petek, Marijan, Turković, Branko, Kokić, Neven, Jagić, Vjekoslav, Boban-Blagaić, Alenka   +18 more
openaire   +4 more sources

Ulcer Healing Effect Of Anti-Ulcer Agents: A Comparative Study

The Internet Journal of Academic Physician Assistants, 2003
P. Dharmani, K. Kumar, S. Srivastava, G. Palit   +3 more
openaire   +2 more sources

Developments in non-anticholinergic anti-ulcer agents

The American Journal of Digestive Diseases, 1970
Since the introduction of belladonna alkaloids, drugs blocking the cholinergic nervous system have dominated therapeutics for peptic ulcer. Until recently, the only modification of this therapy has been the use of synthetic anticholinergic agents.
D E, Butler, R A, Purdon, P, Bass
openaire   +2 more sources

Anti-ulcer agents

2023
This chapter looks at peptic ulcers, which are localized erosions of the mucous membranes and occur in the stomach and duodenum. It analyzes hydrochloric acid (HCl) present in gastric juices which results in increased irritation, noting how drugs that inhibit the release of HCl act as anti-ulcer agents.
openaire   +1 more source

Synthesis of Novel Aryl (4-Aryl-1h-Pyrrol-3-Yl) (Thiophen-2-Yl) Meth-anone Derivatives: Molecular Modelling, In Silico Admet, Anti-Inflammatory and Anti-Ulcer Activities.

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2020
BACKGROUND A series of novel aryl (4-aryl-1H-pyrrol-3-yl) (thiophen-2-yl) methanone derivatives was synthe-sized from sequential addition reaction with chalcones and toluenesulfonylmethyl isocyanide (TosMIC).
A. Pasha, S. Mondal, Naresh Panigrahi
semanticscholar   +1 more source

Overview: Recent Advances in Anti-ulcer Agents

Current Opinion on Therapeutic Patents, 1993
(1993). Overview: Recent Advances in Anti-ulcer Agents. Current Opinion on Therapeutic Patents: Vol. 3, No. 9, pp. 1305-1312.
openaire   +1 more source

Anti-ulcer agents: chemical aspect of solving the problem

Russian Chemical Reviews, 2015
The data on chemical structures and specific activities of compounds functioning as histamine H2-receptor antagonists, H+/K+-ATPase inhibitors at the exchange sites of hydrogen ions (proton pump inhibitors) and potassium ions (K+-competitive acid blockers) published from 1990 to 2013 are surveyed.
L N Rogoza, N F Salakhutdinov
openaire   +1 more source

The anti-ulcer agent, irsogladine, increases insulin secretion by MIN6 cells

European Journal of Pharmacology, 2012
Insulin secretion by pancreatic islets is a multicellular process. In addition to other essential systems, gap junctions are an important component of cell-to-cell communication in pancreatic islets. It is well known that dysfunction of gap junctions causes inappropriate insulin secretion.
Tsuyoshi, Matsumoto, Kenichi, Sakurai, Asami, Tanaka, Takayuki, Ishibashi, Kaori, Tachibana, Ko, Ishikawa, Koutaro, Yokote   +6 more
openaire   +2 more sources

Role of Empiric Anti-Fungal Therapy in the Treatment of Perforated Peptic Ulcer Disease: Review of the Evidence and Future Directions

Surgical Infections, 2019
Background: Peptic ulcer disease (PUD) affects four million people worldwide. Perforated peptic ulcer (PPU) occurs in less than 15% of cases but is associated with significant morbidity and mortality rates.
J. Huston, Laura A. Kreiner, V. Ho, J. Sanders, Therése M. Duane   +4 more
semanticscholar   +1 more source