Nerve cells partially mitigate indomethacin‐induced tight junction dysregulation in neuro‐gut epithelial cell cocultures. Human milk oligosaccharides 2′‐ and 3‐fucosyllactose (2′‐FL and 3‐FL) protect the neuro‐gut epithelial barrier from indomethacin‐induced damage. This protection is stronger in cocultures with higher nerve cell densities.
Xiaochen Chen+3 more
wiley +1 more source
Low Cholesterol Concentrations and the Risk of Peptic Ulcer Bleeding: A Retrospective Cohort Study. [PDF]
Kök M+5 more
europepmc +1 more source
A novel anti-ulcer agent (TEI-5103) direetly acting on the gastric mucosa from lumen
Noboru Yamazaki+6 more
openalex +1 more source
Anti‐Inflammatory and Antibacterial Properties of Curcuma longa Extract Against Helicobacter pylori
This study explored the effects of Curcuma longa extract (CLE) against H. pylori infection. CLE contained 18 chemical compounds and completely inhibited growth of H. pylori Sydney strain 1 (SS1) in vitro. In infected mice with H. pylori SS1, oral administration of CLE successfully eradicated H.
Jeongsook Kim+7 more
wiley +1 more source
Gastric cancer risk after Helicobacter pylori eradication in gastritis and peptic ulcer: a retrospective cohort study in Japan. [PDF]
Sugano K, Suzuki C, Ota M, Iwakiri R.
europepmc +1 more source
The tested Phlomis species are a rich source of bioactive molecules with potential therapeutic applications, and selecting appropriate extraction solvents is crucial for achieving the targeted biological activity. Phlomis species (family Lamiaceae) are highly valued as food and herbal medicine.
Sakina Yagi+8 more
wiley +1 more source
<i>Acanthamoeba</i> keratitis in a tertiary referral hospital in central China: demographics, risk factors, clinical presentation, treatments and outcomes. [PDF]
Wang JS+5 more
europepmc +1 more source
Ibuprofen‐Functionalized Alkyl α‐hydroxy Methacrylate‐Based Polymers
This work describes the synthesis and evaluation of novel alkyl α‐hydroxymethacrylate‐based ibuprofen‐functionalized prodrugs to improve the bioavailability, decrease toxicity, and control drug release. Novel alkyl α‐hydroxymethacrylate‐based prodrugs are prepared to improve bioavailability, decrease toxicity, and control drug release.
Burcu Balaban+6 more
wiley +1 more source
Network Pharmacology and Experimental Validation Reveal Sishen Pill's Efficacy in Treating NSAID-Induced Small Intestinal Ulcers. [PDF]
Zhou J, Zhu F, Liang H, Sun L.
europepmc +1 more source