Results 321 to 330 of about 397,771 (348)
Some of the next articles are maybe not open access.
2023
This chapter looks at peptic ulcers, which are localized erosions of the mucous membranes and occur in the stomach and duodenum. It analyzes hydrochloric acid (HCl) present in gastric juices which results in increased irritation, noting how drugs that inhibit the release of HCl act as anti-ulcer agents.
openaire +1 more source
This chapter looks at peptic ulcers, which are localized erosions of the mucous membranes and occur in the stomach and duodenum. It analyzes hydrochloric acid (HCl) present in gastric juices which results in increased irritation, noting how drugs that inhibit the release of HCl act as anti-ulcer agents.
openaire +1 more source
The anti-ulcer agent, irsogladine, increases insulin secretion by MIN6 cells
European Journal of Pharmacology, 2012Insulin secretion by pancreatic islets is a multicellular process. In addition to other essential systems, gap junctions are an important component of cell-to-cell communication in pancreatic islets. It is well known that dysfunction of gap junctions causes inappropriate insulin secretion.
Kaori Tachibana +6 more
openaire +3 more sources
Inhibition of gastric H+,K+-ATPase by the anti-ulcer agent, sofalcone
Biochemical Pharmacology, 1991Effects of the anti-ulcer agent, sofalcone, on gastric H+,K(+)-ATPase were studied as well as those of other chalcone derivatives, chalcone and sophoradin. These drugs inhibited pig gastric H+,K(+)-ATPase in a dose-dependent manner. They were 5-10-fold less inhibitory toward Na+,K(+)-ATPase than H+,K(+)-ATPase.
Murakami Shigeru +3 more
openaire +3 more sources
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2020
BACKGROUND A series of novel aryl (4-aryl-1H-pyrrol-3-yl) (thiophen-2-yl) methanone derivatives was synthe-sized from sequential addition reaction with chalcones and toluenesulfonylmethyl isocyanide (TosMIC).
A. Pasha, S. Mondal, Naresh Panigrahi
semanticscholar +1 more source
BACKGROUND A series of novel aryl (4-aryl-1H-pyrrol-3-yl) (thiophen-2-yl) methanone derivatives was synthe-sized from sequential addition reaction with chalcones and toluenesulfonylmethyl isocyanide (TosMIC).
A. Pasha, S. Mondal, Naresh Panigrahi
semanticscholar +1 more source
Pharmacology, 1987
Psychological stress produced by intraspecies emotional communication in a communication box was studied to see whether it could be applied to a new screening method for anti-ulcer agents.
Y. Ichimaru, Y. Gomita
semanticscholar +1 more source
Psychological stress produced by intraspecies emotional communication in a communication box was studied to see whether it could be applied to a new screening method for anti-ulcer agents.
Y. Ichimaru, Y. Gomita
semanticscholar +1 more source
Overview: Recent Advances in Anti-ulcer Agents
Current Opinion on Therapeutic Patents, 1993(1993). Overview: Recent Advances in Anti-ulcer Agents. Current Opinion on Therapeutic Patents: Vol. 3, No. 9, pp. 1305-1312.
openaire +2 more sources
Pharmacological Evaluation of Saccharum Officinarum Linn. as Anti-ulcer Agent
International Journal of Science, Technology & Society, 2018The purpose of the study was to elucidate the antiulcer activity of stem of Saccharum Officinarum (Poaceae) in albino rats against aspirin induced gastric ulcer, ethanol induced gastric ulcer and pylorus ligation induced gastric ulcer models. Groups of rats were fasted overnight, received ranitidine (20 mg/kg) as a standard and plant stem juice extract
Preksha Dwivedi +3 more
openaire +2 more sources
Ulcer Healing Effect Of Anti-Ulcer Agents: A Comparative Study
, 2002Gastric ulcer being the most prevalent gastrointestinal disorder is considered as a major therapeutic target. Large numbers of drugs ranging from proton pump inhibitors, H2 receptor antagonists to cytoprotective agents are being used for treatment of ...
P. Dharmani +3 more
semanticscholar +1 more source
Advanced Materials Research, 2014
A pair of triazole-linked bistetrahydrobenzofuran derivatives were prepared in high yields through Cu (II)-catalyzed click reaction under mild conditions. All of the intermediates and target compounds were characterized by NMR, IR, ESI-MS and elemental analysis. The in vitro H+/K+-ATPase inhibitory effect for the target compounds were also evaluated by
Hu Biao Fang +5 more
openaire +2 more sources
A pair of triazole-linked bistetrahydrobenzofuran derivatives were prepared in high yields through Cu (II)-catalyzed click reaction under mild conditions. All of the intermediates and target compounds were characterized by NMR, IR, ESI-MS and elemental analysis. The in vitro H+/K+-ATPase inhibitory effect for the target compounds were also evaluated by
Hu Biao Fang +5 more
openaire +2 more sources
Journal of Chromatography B: Biomedical Sciences and Applications, 1982
A highly specific and sensitive method for the determination of the anti-ulcer drug geranylgeranylacetone (GGA) in human serum is described. The extract from serum with hexane was saponified with potassium hydroxide and subjected to silica gel column chromatography to remove interfering substances. GGA in the partially purified extract was then reacted
Michiru Tanaka +3 more
openaire +3 more sources
A highly specific and sensitive method for the determination of the anti-ulcer drug geranylgeranylacetone (GGA) in human serum is described. The extract from serum with hexane was saponified with potassium hydroxide and subjected to silica gel column chromatography to remove interfering substances. GGA in the partially purified extract was then reacted
Michiru Tanaka +3 more
openaire +3 more sources