Results 51 to 60 of about 1,966,260 (257)

The values and anti-values of the shadow economy

open access: yesRussian Journal of Legal Studies, 2015
The article analyzes the risk of criminal manifestations of the shadow economy, and shown their devastating effects not only on the legal economy, and through it - on politics, social sphere, culture and law. The conclusion is, that due to the significant weakening of this reason, economic, political, social, cultural and legal institutions, the focus ...
openaire   +2 more sources

Concept of PRIDE in Comic Discourse: Axiological Approach

open access: yesНаучный диалог
This article examines the peculiarities of the actualization of the concept of PRIDE within comic discourse from the perspective of axiological linguistics.
A. I. Bochkarev
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Implementation of Anti-Corruption Values Through Extracurricular Activities in Elementary School: Literature Reviews

open access: yesEducation Human and Development Journal, 2022
: This study aims to systematically review articles on the implementation of anti-corruption values ​​through extracurricular activities in elementary schools from 2018-to 2022.
Rr. Fadila Kusumaning Ayu   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Strategi Pendidikan Anti Korupsi pada Jenjang Sekolah Dasar

open access: yesASANKA, 2021
The Anti-Corruption Education Strategy is a very crucial thing in Indonesia. Many cases of corruption that occur in this country ranging from small cases to large cases and harm the country. Therefore, it is necessary to instill anti-corruption education
Choirul Anwar
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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