An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang +8 more
wiley +1 more source
Outcomes of Anti-VEGF Therapy in Eyes with Diabetic Macular Edema, Vein Occlusion-Related Macular Edema, and Neovascular Age-Related Macular Degeneration: A Systematic Review [PDF]
Laila Salah Aldokhail,1 Abdulaziz Mohammad Alhadlaq,2 Lujain Mohamed Alaradi,1 Lamees Mohamed Alaradi,1 Fatimah Yaseen AlShaikh1 1Department of Ophthalmology, College of Medicine, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia ...
Aldokhail LS +3 more
core
Peripheral immune dynamics during treatment predict prognosis in HCC receiving TACE plus ICIs and anti-VEGF/TKIs. [PDF]
Qin L +6 more
europepmc +1 more source
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens +11 more
wiley +1 more source
Capillary-Large Vessel Segmentation on OCTA for Predicting Anti-VEGF Treatment Outcomes in Diabetic Macular Edema. [PDF]
Huang RB +7 more
europepmc +1 more source
Anti-VEGF drugs in the prevention of blindness.
Disorders of the blood vessels in the retina are responsible for some of the most common causes of blindness in the world.
openaire +2 more sources
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Outcomes of Selective Laser Trabeculoplasty for Sustained Elevation of Intraocular Pressure Following Intravitreal Anti-VEGF Injections. [PDF]
Jung K, Adelman RA, Liu J.
europepmc +1 more source
Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye +6 more
wiley +1 more source
Systemic and ocular complications related to intravitreal administration of anti-VEGF agents. [PDF]
Koksaldi S +3 more
europepmc +1 more source

