Anti-vascular endothelial growth factor therapies in ophthalmology. [PDF]
Background: Retinal diseases, including neovascular age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion, are leading causes of vision loss worldwide. The introduction of anti-vascular endothelial growth factor (anti-VEGF) therapies has dramatically changed the management of these conditions, offering targeted treatment ...
Koksaldi S, Karti O, Saatci AO.
europepmc +4 more sources
Newer anti-vascular endothelial growth factor agents
Ocular angiogenesis is a major cause of ocular morbidity worldwide. Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis and vascular permeability with diverse roles both during the development and adulthood. This is believed
Priya Rasipuram Chandrasekaran
doaj +2 more sources
Pleurodesis Is Inhibited by Anti-Vascular Endothelial Growth Factor Antibody
The intrapleural injection of transforming growth factor (TGF)-beta2 produces pleurodesis in rabbits associated with large pleural effusions. This study investigated whether anti-vascular endothelial growth factor (VEGF) antibody has any effect on the fluid production or the pleurodesis induced by TGF-beta2.Three groups of seven New Zealand white ...
Ioannis Kalomenidis, Richard W Light
exaly +4 more sources
Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders
Vascular endothelial growth factors (VEGFs) are key mediator of retinal and choroidal neovascularization as well as retinal vascular leakage leading to macular edema.
Abraham Hang +4 more
doaj +3 more sources
Anti-Vascular Endothelial Growth Factor Combined with Dexamethasone Implant Therapy for Macular Edema: A Randomized Controlled Trial [PDF]
Yunxi Ma, Junwen Wang, Mingzhu Yuan, Zimeng Zeng, Yuhe Tan, Lu Cao, Xufang Sun Department of Ophthalmology, Hubei Key Laboratory of Otolaryngologic and Ophthalmic Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and ...
Ma Y +6 more
doaj +2 more sources
Anti-Vascular Endothelial Growth Factor Therapy in Breast Cancer
Neo-angiogenesis is a critical process for tumor growth and invasion and has become a promising target in cancer therapy. This manuscript reviews three currently relevant anti-angiogenic agents targeting the vascular endothelial growth factor system: bevacizumab, ramucirumab and sorafenib. The efficacy of anti-angiogenic drugs in adjuvant therapy or as
Markus Wehland +2 more
exaly +4 more sources
Anti-cancer effects of F16: A novel vascular endothelial growth factor receptor–specific inhibitor
Vascular endothelial growth factor receptor-2 is a dynamic target for therapeutic intervention in various types of cancers. This study was aimed to explore the anti-angiogenic activity of a novel vascular endothelial growth factor receptor–specific ...
Appu Rathinavelu +3 more
doaj +2 more sources
Anti-vascular endothelial growth factor in ophthalmology
Sinha Rajesh +4 more
doaj +2 more sources
Anti-vascular endothelial growth factor for neovascular glaucoma [PDF]
Neovascular glaucoma (NVG) is a potentially blinding secondary glaucoma. It is caused by the formation of abnormal new blood vessels which prevent normal drainage of aqueous from the anterior segment of the eye. Anti-vascular endothelial growth factor (anti-VEGF) agents are specific inhibitors of the primary mediators of neovascularization.
Arathi, Simha +4 more
openaire +4 more sources
Biomarkers for anti‑vascular endothelial growth factor drugs
Angiogenesis is regulated by interactions between vascular endothelial growth factors (VEGFs) and VEGF receptors. VEGF-A, VEGF-D, placental growth factor (PlGF) and plasminogen activator inhibitor-1 (PAI-1) have tumor angiogenic activity. VEGF-A and PAI-1 levels in the blood may impact the activity of bevacizumab, and VEGF-D levels may similarly ...
Kuriyama, Sho +14 more
openaire +2 more sources

