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Anti-vascular endothelial growth factor treatment for eye diseases [PDF]
BMJ, 2012 Treatment is clearly effective but important clinical and public health implications ...
Wong, TY, Cheung, N, Lam, DSC
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Anti Vascular Endothelial Growth Factor Agents in Corneal Neovascularization
Delhi Journal of Ophthalmology, 2011 Corneal neovascularisation is a potentially blinding condition, an established risk factor for rejection and results in loss of immune privilege. It may occur as a normal physiologic healing response to various stimuli or as an inappropriate local tissue
Srivatsa Sehra, Reetika
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International Breastfeeding Journal, 2022 Background Ranibizumab is one of intravitreal anti-vascular endothelial growth factor agents. It is applied in the treatments of choroidal neovascularization, age-related macular degeneration, diabetic macular edema, and macular edema secondary to ...
Ying Huang +4 more
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Ten years of anti-vascular endothelial growth factor therapy [PDF]
Nature Reviews Drug Discovery, 2016 The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both normal and pathological angiogenesis, has revealed innovative therapeutic approaches in oncology and ophthalmology. The first VEGFA inhibitor, bevacizumab, was approved by the US Food and Drug Administration in 2004 for the first-line treatment of metastatic ...
Ferrara, Napoleone, Adamis, Anthony P
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Acta Pharmaceutica, 2022 Statins have shown anti-inflammatory pleiotropic effects in subjects with/at risk of cardiovascular disease. The aim of this study was to evaluate the inflammatory/immunomodulatory properties of rosuvastatin in subjects at low-to-moderate cardiovascular ...
VAVLUKIS ANA +6 more
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Newly Identified Peptide, Peptide Lv, Promotes Pathological Angiogenesis
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background We recently discovered a small endogenous peptide, peptide Lv, with the ability to activate vascular endothelial growth factor receptor 2 and its downstream signaling.
Liheng Shi +12 more
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IJU Case Reports, 2023 Introduction Renal cell carcinoma with TFEB amplification is rare and reportedly aggressive. We herein report a case of renal cell carcinoma with TFEB translocation and amplification in which long‐term control was achieved by multimodal therapy including
Hajime Takamori +5 more
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Anti-vascular endothelial growth factor therapy for malignant glioma [PDF]
Current Neurology and Neuroscience Reports, 2009 Glioblastomas are among the most vascular tumors because they oversecrete vascular endothelial growth factor (VEGF), a potent stimulator of angiogenesis. Consequently, new drug regimens are being developed to target the VEGF signaling pathway in an attempt to halt tumor growth.
Elizabeth R, Gerstner +3 more
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Immunohistochemical Expression of Vascular Endothelial Growth Factor and Its Correlation With Tumor Grade in Breast Ductal Carcinoma [PDF]
Acta Medica Iranica, 2011 Breast cancer is the most common cause of cancer-related death in female, after lung cancer. Angiogenesis is essential for tumor growth and metastasis; therefore, antiangiogenesis strategies for treatment of cancer are currently an issue of interest. The
Laleh Vahedi Larijani +6 more
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Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
Frontiers in Pharmacology, 2020 Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen +4 more
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