Results 11 to 20 of about 11,095,042 (285)
Angioid streaks, a rare defect of Bruch’s membrane, are most typically characterized by an asymptomatic course. However, when complications such as submacular hemorrhage or a neovascular membrane develop, visual acuity may deteriorate markedly, requiring
Karolina Agnieszka Korycińska +2 more
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Diabetes is a major cause of visual impairment among workingage adults in the United States. The proliferative form of diabetic retinopathy is associated with severe vision loss (acuity
Yue Zhao, Rishi P Singh
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Jong Hwa Jun,1 Wern-Joo Sohn,2 Youngkyun Lee,2 Jae-Young Kim21Department of Ophthalmology, School of Medicine, Dongsan Medical Center, Keimyung University, 2Department of Oral Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu,
Jun JH, Sohn WJ, Lee Y, Kim JY
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Anti-cancer effects of F16: A novel vascular endothelial growth factor receptor–specific inhibitor
Vascular endothelial growth factor receptor-2 is a dynamic target for therapeutic intervention in various types of cancers. This study was aimed to explore the anti-angiogenic activity of a novel vascular endothelial growth factor receptor–specific ...
Appu Rathinavelu +3 more
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Epiretinal membrane is a type of fibrous proliferation on the retinal surface in the macular region. Its most common symptoms include metamorphopsia, micropsia, macropsia, and reduced visual acuity. When these symptoms are present, patients are typically
Paulina Glasner +2 more
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Vascular Targeted Agents for the Treatment of Angiosarcoma [PDF]
Background: Angiogenesis is the process of new blood vessel formation, and is regulated by angiogenic growth factors including vascular endothelial growth factor (VEGF). Angiosarcomas are rare, aggressive vascular tumours.
P J Woll (16226153) +5 more
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Anti-vascular endothelial growth factor in ophthalmology
Sinha Rajesh +4 more
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Szilárd Kiss,1 Ying Liu,2 Joseph Brown,3 Nancy M Holekamp,4,5 Arghavan Almony,6 Joanna Campbell,2 Jonathan W Kowalski2 1Weill Cornell Medical College, New York, NY; 2Allergan, Inc., Irvine, CA; 3IMS Health, Woodland Hills, CA; 4Pepose Vision ...
Kiss S +6 more
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Anti-vascular endothelial growth factor for neovascular glaucoma [PDF]
Neovascular glaucoma (NVG) is a potentially blinding secondary glaucoma. It is caused by the formation of abnormal new blood vessels which prevent normal drainage of aqueous from the anterior segment of the eye. Anti-vascular endothelial growth factor (anti-VEGF) agents are specific inhibitors of the primary mediators of neovascularization.
Arathi, Simha +4 more
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Biomarkers for anti‑vascular endothelial growth factor drugs
Angiogenesis is regulated by interactions between vascular endothelial growth factors (VEGFs) and VEGF receptors. VEGF-A, VEGF-D, placental growth factor (PlGF) and plasminogen activator inhibitor-1 (PAI-1) have tumor angiogenic activity. VEGF-A and PAI-1 levels in the blood may impact the activity of bevacizumab, and VEGF-D levels may similarly ...
Kuriyama, Sho +14 more
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