Results 111 to 120 of about 100,511 (312)

Anti‐cancer drugs targeting the NADH‐binding site of VDAC rewire channel electrophysiology and partially suppress cation selectivity

open access: yesThe FEBS Journal, EarlyView.
VA molecules alter VDAC1 gating by increasing anion flow and reducing cation permeability. In cancer cells, which rely on ER‐mitochondria Ca2+ transfer and overexpress VDAC1, this imbalance triggers bioenergetic stress, ROS buildup, and mitochondrial collapse, leading to cell death.
Stefano Conti‐Nibali   +6 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

A Comprehensive Assessment of Renal Function During and After Pulsed Field Ablation

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Acute kidney injury is an uncommon complication of pulsed field ablation (PFA). There is, however, limited empirical data on the dynamics of renal biomarkers apart from creatinine. Furthermore, no study to date has assessed creatinine at more than 24 h after the procedure. Methods Patients undergoing PFA for atrial fibrillation (AF)
Václav Melenovský   +10 more
wiley   +1 more source

Epilepsy Is a Risk Factor for Sudden Cardiac Arrest in the General Population [PDF]

open access: yes, 2012
Background People with epilepsy are at increased risk for sudden death. The most prevalent cause of sudden death in the general population is sudden cardiac arrest (SCA) due to ventricular fibrillation (VF). SCA may contribute to the increased incidence
Bardai, A   +10 more
core   +1 more source

Characterization of AV Nodal Left Inferior Extension by Use of High‐Density Mapping and Voltage‐Time Relationship

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
High resolution voltage LA map is shown with Ripple mapping during sinus rhythm prior to atrial fibrillation ablation (panel A‐D, top row Left Anterior Oblique view, bottom row Left Anterior Oblique Caudal view). Chamber activation is visualized by white Ripple bars, proceeding from the septum and septal roof (panel A), spreading clockwise and ...
June K. Pickett   +8 more
wiley   +1 more source

Non-valvular atrial fibrillation and stroke : implications for management [PDF]

open access: yes, 1995
Nonvalvular Atrial Fibrillation is more prevalent with increasing age. It is associated with a six-fold excess risk of stroke; and a cumulative lifetime stroke risk of 35%. 15% of ischaemic strokes are directly attributable to it.
Tilney, Myra Kay
core  

Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.

open access: yesJournal of the American College of Cardiology, 1996
OBJECTIVES We examined the modulatory effects of autonomic nervous system and antiarrhythmic drugs on the ST segment in patients with Brugada syndrome to gain an insight into the mechanism of ST segment elevation.
Toshihisa Miyazaki   +5 more
semanticscholar   +1 more source

Sustained Idiopathic Outflow Tract Ventricular Tachycardia: Clinical Evidence for RVOT Predominance

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Idiopathic outflow tract premature ventricular contractions (PVCs) are most commonly localized in the right ventricular outflow tract (RVOT). The clinical significance of sustained outflow tract ventricular tachycardia (OT‐VT) regarding any predominance to one specific anatomic area remains uncertain.
Moneeb Khalaph   +16 more
wiley   +1 more source

Left Atrial Posterior Wall Functional Remodeling in Paroxysmal and Persistent Atrial Fibrillation. A Pilot Study

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background The left atrial posterior wall (LAPW) is often targeted in atrial fibrillation (AF) ablation due to its shared properties with pulmonary veins. However, substrate‐guided approaches using structural markers have shown inconsistent results.
Michael M. Malaty   +7 more
wiley   +1 more source

Proarrhythmic Antiarrhythmic [PDF]

open access: yesTexas Heart Institute Journal, 2016
Mark, Pollet, Mohammad, Saeed
openaire   +2 more sources

Home - About - Disclaimer - Privacy