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Atrial Fibrillation: Antiarrhythmic Therapy

Current Problems in Cardiology, 2014
Atrial fibrillation is the most common cardiac arrhythmia and is associated with significant morbidity, mortality, and economic cost. Although the benefit of anticoagulation has been well described, control of the underlying rhythm disturbance can be achieved in various ways. Numerous therapeutic options exist and continue to be developed; however, the
Mitchell A, Psotka, Byron K, Lee
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Future Trends in Antiarrhythmic Therapy

Journal of Cardiovascular Pharmacology, 1991
It is difficult to define what the trends will be in antiarrhythmic therapy in the coming years, particularly at a time when rhythmology has been somewhat destabilized by the unexpected results of large therapeutic trials on sudden death prevention. Schematically, drugs that do have established antiarrhythmic properties do not provide any benefit, and ...
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Therapy with Investigational Antiarrhythmic Drugs

Medical Clinics of North America, 1984
The investigational antiarrhythmic agents available for use in this country are predominantly class I drugs with local anesthetic membrane effects. These drugs are often used successfully to control arrhythmias refractory to treatment with the standard antiarrhythmic drugs.
R H, Mead, D C, Harrison
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Current antiarrhythmic therapy overview

Cardiovascular Drugs and Therapy, 1990
Cardiac arrhythmias are commonplace in the Western world and vary in their degree of seriousness from benign to life threatening. In general, arrhythmias may be managed in one of five ways: reassurance only, physical maneuvers, antiarrhythmic drugs, implantable electronic devices, and surgical or transvascular ablation.
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Antiarrhythmic therapy in atrial fibrillation

Pharmacology & Therapeutics, 2010
Currently available antiarrhythmic drugs for the management of AF are not sufficiently effective and are burdened with cardiac and extracardiac side effects that may offset their therapeutic benefits. Better knowledge about the mechanisms underlying generation and maintenance of AF may lead to the discovery of new targets for pharmacological ...
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New Approaches to Antiarrhythmic Therapy

New England Journal of Medicine, 1981
Concepts of antiarrhythmic therapy have undergone major changes in the past decade for a variety of reasons. First of all, electrophysiologic studies — ushered in by the observation1 that His-bundle activation could be recorded simply, safely, and reliably in human beings — have progressed from academic, research-oriented tools providing important data
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Advances in Antiarrhythmic Drug Therapy

1992
Publisher Summary Recently, electrophysiologic studies have suggested that the arrhythmias leading to sudden cardiac death may have a different mechanism and pathophysiology from those producing frequent premature ventricular contractions. This has led to the speculation that agents that affect the duration of the action potential and His-Purkinje ...
D C, Harrison, M B, Bottorff
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Antiarrhythmic Therapy for Ventricular Arrhythmias

Journal of Cardiovascular Pharmacology, 1991
Treatment of ventricular arrhythmias has received great attention during the past 20 years. However, results of recent trials with class I antiarrhythmic drugs in patients after myocardial infarction have raised many questions about the risk-benefit ratio of antiarrhythmic therapy, at least in asymptomatic subjects.
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Antiarrhythmic Drug Therapy

The American Journal of Nursing, 1980
J L, Stanford, J M, Felner, D, Arensberg
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Amiodarone in the antiarrhythmic therapy

Pharmacological Research Communications, 1983
F, Furlanello   +5 more
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