Results 121 to 130 of about 8,495 (251)

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Response by Rogers et al to Letter Regarding, "Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation". [PDF]

Circulation
Rogers AJ, Bandyopadhyay S, Ansari RA.
europepmc   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, Volume 13, Issue 51, 14 September 2026.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2151-2156, September 2026.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

BRET‐Based Approaches for Ion Channels: Emerging Applications and Future Directions

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
Bioluminescence resonance energy transfer (BRET) is a versatile method for studying ligand–protein interactions. Its compatibility with high‐throughput screening and real‐time kinetics has made it widely used in drug discovery. Here, we summarize recent applications of BRET‐based methods for studying ligand binding to ion channels, highlighting key ...
Nadine Kock, Laura Heitzer, Joana Massa, Marvin Taterra, Marcel Bermúdez, Oliver Koch, Matthias Schiedel   +6 more
wiley   +1 more source

The Impact of a Visualized Steerable Sheath on Radiofrequency Catheter Ablation for First‐Time Atrial Fibrillation Ablation: A Prospective, Randomized, Single‐Blind Study

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 924-934, September 1, 2026.
ABSTRACT Background A 3D electroanatomical mapping (3D‐EAM) visualized steerable sheath was designed to improve catheter placement and reduce radiation exposure during ablation, an established treatment for atrial fibrillation (AF). However, prospective randomized data comparing the procedural and clinical outcomes of visualized and non‐visualized ...
Chun‐Kai Chen, Chih‐Chieh Yu, Min‐Tsun Liao, Hui‐Chun Huang, Yen‐Bin Liu   +4 more
wiley   +1 more source

Beyond the review: additional non-oncologic drugs with clinically significant cardiovascular effects. [PDF]

Eur Heart J Cardiovasc Pharmacother
Van der Linden L, Vanassche T.
europepmc   +1 more source

Combined Application of a Helix‐Fixation Leadless Pacemaker and a Subcutaneous Implantable Cardioverter‐Defibrillator in a Dialysis Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Combined use of S‐ICD and LP provides an effective alternative for patients requiring defibrillation and pacing while avoiding transvenous leads. This strategy is particularly valuable for patients with a high risk of infection, though careful consideration must be given to minimizing potential device–device interactions.
ZhaoWei Zhou, Wenbo Zhang, Jie Pang, Ying Zhou   +3 more
wiley   +1 more source

Association of Transition Zone Burden With Recurrence in Elderly Patients With Paroxysmal Atrial Fibrillation Without Low‐Voltage Areas

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Transition zone (TZ) is defined as regions with bipolar voltage between 0.5 and 1 mV in left atrium. In 158 elderly PAF patients without low‐voltage areas (LVA), TZ burden is associated with reduced left atrial conduction velocity (LACV) and independently predicts atrial tachyarrhythmia (ATA) recurrence following CPVI.
Yuxuan Wang, Yue Qiu, Haojun Wang, Chang Cui, Zidun Wang, Xiaohong Jiang, Mingfang Li, Juejin Wang, Hongwu Chen, Minglong Chen   +9 more
wiley   +1 more source

Skin Sympathetic Nerve Activity After Pulsed Field Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation: The NEU-PFA Study. [PDF]

Circ Arrhythm Electrophysiol
Ling LC, Lo LW, Chung FP, Chang SL, Hu YF, Lin CY, Chang TY, Kuo L, Liu CM, Liu SH, Wu CI, Lin YJ, Hsieh YC, Li CH, Kuo MJ, Wu SJ, Lee GY, Huang YS, Chien YS, Chan CH, Phang YH, Nguyen QH, Le XH, Ong N, Chang DW, Chen SA.   +25 more
europepmc   +1 more source