Results 121 to 130 of about 44,802 (314)

Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To determine the cardiovascular and respiratory effects of bolus IV isotonic crystalloid fluid therapy before pericardiocentesis in dogs with pericardial effusion. Design Prospective, randomized, nonblinded clinical trial (January 2021 to November 2022). Setting University teaching hospital.
Nadine Jones   +2 more
wiley   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou   +11 more
wiley   +1 more source

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation.

open access: yesCochrane Database of Systematic Reviews, 2015
C. Lafuente-Lafuente   +3 more
semanticscholar   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Modern views on myocardial electric instability correction and prognosis improvement in coronary heart disease patients

open access: yesКардиоваскулярная терапия и профилактика, 2007
Sudden cardiac death (SCD) remains the principal cause of coronary heart disease (CHD) deaths. Therefore, studying SCD mechanisms, implementing new prognostic and preventive approaches are the main aims of modern cardiology.
V. V. Popov, A. E. Radzevich
doaj  

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier   +3 more
wiley   +1 more source

Chemistry, physiology, and pharmacology of β-adrenergic mechanisms in the heart. Why are β-blocker antiarrhythmics superior?

open access: yesCurrent pharmaceutical design, 2014
J. Szentmiklósi   +6 more
semanticscholar   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach   +8 more
wiley   +1 more source

Fluoxetine Blocks Nav1.5 Channels via a Mechanism Similar to That of Class 1 Antiarrhythmics

open access: yesMolecular Pharmacology, 2014
Hugo Poulin   +6 more
semanticscholar   +1 more source

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