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Reactions WeeklyAbstract Antiarrhythmics are divided into four main Vaughan-Williams classifications based on their primary actions on the myocardial cell action potential (AP). The different classes of drugs exert their action on different phastes of the cardiac AP. New drugs and actions have become available or are being researched, including class 0,
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Current Drug Metabolism, 2004 Antiarrhythmics are a group of drugs that manage the irregular electrical activity of the heart. Their use in the clinic is made difficult by their narrow therapeutic index. The disposition of antiarrhythmics is dependent on many factors, such as administration route, stereoselectivity in the first-pass effect, inhibition of enzymes, polymorphisms, etc.
Ha HR, Follath F
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Antiarrhythmics in Cardiac Arrest: A Systematic Review and Meta-Analysis
Heart Lung and Circulation, 2018 Introduction: It is widely accepted that antiarrhythmics play a role in cardiopulmonary resuscitation (CPR) universally, but the absolute benefit of antiarrhythmic use and the drug of choice in advanced life support remains controversial. Aim: To perform
Brian Fernandes, Leigh D White
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, 2018 Antiarrhythmic drugs are the cornerstone of supraventricular and ventricular arrhythmias therapy. Despite the increasing interest in invasive and ablative approaches to treating many arrhythmias, such as atrial fibrillation and ventricular tachycardia ...
Mathew George, Lincy Joseph, Sujith K
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Current Opinion in Cardiology, 1991
Medically refractory tachyarrhythmias remain a significant clinical problem. The indications for surgical intervention in this challenging patient population continue to expand. Advances in noninvasive detection of patients at risk, as well as expanding electrophysiologic testing, continue to help define patients best served by surgical therapy ...
M A, Grosso, A H, Harken
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Medically refractory tachyarrhythmias remain a significant clinical problem. The indications for surgical intervention in this challenging patient population continue to expand. Advances in noninvasive detection of patients at risk, as well as expanding electrophysiologic testing, continue to help define patients best served by surgical therapy ...
M A, Grosso, A H, Harken
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Current Treatment Options in Cardiovascular Medicine, 2004
Both supraventricular and ventricular arrhythmias are associated with increased mortality and morbidity. Numerous antiarrhythmics have been developed in an attempt to decrease the frequency of these arrhythmias, hoping to improve survival and improve quality of life.
Steven N., Singh +2 more
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Both supraventricular and ventricular arrhythmias are associated with increased mortality and morbidity. Numerous antiarrhythmics have been developed in an attempt to decrease the frequency of these arrhythmias, hoping to improve survival and improve quality of life.
Steven N., Singh +2 more
openaire +2 more sources