Results 121 to 130 of about 577,991 (307)

Economic Burden of Uncontrolled COPD Under Triple Therapy: A Population-Based Study

International Journal of COPD
Nicolas Molinari,1 Nicolas Roche,2 Anne-Lise Vataire,3 Stanislas Perrier,3 Nicolas Pagès,4 Arnaud Panes,4 Aurélie Schmidt,4 Arnaud Bourdin,5,6 Laurence Watier7 1IDESP, INSERM, PreMEdical INRIA, Univ Montpellier, CHU Montpellier, Montpellier, France ...
Molinari N, Roche N, Vataire AL, Perrier S, Pagès N, Panes A, Schmidt A, Bourdin A, Watier L   +8 more
doaj  

Reducing Peptidoglycan Crosslinking by Chemical Modulator Reverts β‐lactam Resistance in Methicillin‐Resistant Staphylococcus aureus

Advanced Science
Small molecule can be utilized to restore the effectiveness of existing major classes of antibiotics against antibiotic‐resistant bacteria. In this study, it is demonstrated that celastrol, a natural compound, can modify the bacterial cell wall and ...
Ji‐Hoon Kim, Yunmi Lee, Inseo Kim, JuOae Chang, Subin Hong, Na Kyung Lee, David Shum, Seongeun Baek, Wooseong Kim, Soojin Jang, Wonsik Lee   +10 more
doaj   +1 more source

Quantitative determination and antibacterial properties of TiO2 nanoparticle-doped glass ionomer cement: an in vitro study

European Oral Research
Purpose: The aim of the present study is to determine the amount of titanium ions released into the artificial salivary medium by modified glass ionomer cement (GIC) doped with 3% and 5% (w/w) titanium dioxide nanoparticles (TiO2-NPs), and to evaluate ...
Tivanani V D Mahendra, Tavva Santhosh Rahul, Santosh Venkata Ramesh Konathala, P Swetha, V Sai Sai Keerthi, Vyshnavi M   +5 more
doaj   +1 more source

Antibacterial Activity of Lactuca virosa with an In silico Approach [PDF]

The current work aims to screen the phytoconstitutes of the Lactuca virosa leaves ethanolic extract by using GC-MS analysis and investigate its antibacterial activity. GC-MS analysis was conducted to identify the various phytochemical constituents within
Rajesh Kumar Rawri, C K Prasanna, Paramita Das, Darshan Neelagund   +3 more
core   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Kidney‐Targeted Cilastatin Nanoparticles Inhibit DPEP1‐Mediated Ferroptosis for Acute Kidney Injury Therapy

Advanced Science, EarlyView.
In this study, MPDA NPs were engineered to encapsulate CTT. To further increase renal accumulation of CTT, L‐serine was conjugated to the surface of the MPDA nanoparticles (CTT/MPDA@L‐Ser NPs). CTT/MPDA@L‐Ser NPs inhibit DPEP1 activity, thereby restoring ferroptosis defense mechanisms through upregulation of GPX4 and SLC7A11 expression, ultimately ...
Wanbing Qin, Jiaqi Huang, Manting Zhang, Wanchun Yang, Mingwei Xu, Chi Jiang, Jiekai Li, Jinjuan Wen, Qibin Huang, Shiqi Wen, Weidong Wang, Junbing He, Qinghua Liu   +12 more
wiley   +1 more source

Antibacterial test of various ingredients of “Indonesian Jamu” [PDF]

, 2019
Jamu is an Indonesian traditional beverage, made from various Indonesian spices, and believed to possess antibacterial properties. The aim of this research was to determine whether typical Indonesian Jamu ingredients had antibacterial compounds.
Nabela Nur Hanifah, .-, Nurul ‘Aini,, .-, Tri Rahayu,, .-, Indra Adi Wira Prasetya,, .-, Mar’atus Sholichah,, .-, Lisa Marjayandari,, .-, Izdihar Tsana,, .-, Fatimah,, .-, Ana Mariatul Khiftiyah,, .-, Selva Rosyta Dewi, .-, Desi Triwahyuni,, .-, Muhammad Bachruddin,, .-, Siti Istiqomah,, .-, Ni’matuzahroh   +13 more
core   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source

Advanced surface modification techniques for titanium implants: a review of osteogenic and antibacterial strategies

Frontiers in Bioengineering and Biotechnology
Titanium (Ti) implants are widely used in orthopedic and dental applications due to their excellent mechanical strength, corrosion resistance, and biocompatibility. However, their limited osteointegration and susceptibility to bacterial infections remain
Handong Zhang, Zidong Wu, Zemin Wang, Xinfeng Yan, Xudong Duan, Huaqiang Sun   +5 more
doaj   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source