Results 31 to 40 of about 273,307 (263)

Fabrication and evaluation magnetic nanoparticles loaded with cefixime

Journal of Contemporary Pharmacy, 2021
Background. Bacterial infections are an important cause of serious health issues worldwide. Various antibacterial drugs have been developed but they have numerous side effects.
Kanza Amjad, Ume Habiba, Talib Hussain, Safiullah Khan, Muhammad Akram Choohan   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Cu2+ Inhibits the Peroxidase and Antibacterial Activity of Homodimer Hemoglobin From Blood Clam Tegillarca granosa by Destroying Its Heme Pocket Structure

Frontiers in Marine Science, 2021
Beyond its role as an oxygen transport protein, the homodimer hemoglobin of blood clam Tegillarca granosa (Tg-HbI) has been found to possess antibacterial activity. However, the mechanism of antibacterial activity of Tg-HbI remain to be investigated.
Sufang Wang, Xiaopei Yu, Shunqin Zhang, Hongyu Jin, Zhongfa Chen, Zhihua Lin, Yongbo Bao   +6 more
doaj   +1 more source

Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones [PDF]

Molecules, 2017
Cinnamaldehyde is a natural product with broad spectrum of antibacterial activity. In this work, it was used as a template for design and synthesis of a series of 17 cinnamylideneacetophenones. Phenolic compounds 3 and 4 exhibited MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration) values of 77.9 to 312 µM against ...
Carlos Polaquini, Guilherme Torrezan, Vanessa Santos, Ana Nazaré, Débora Campos, Laíza Almeida, Isabel Silva, Henrique Ferreira, Fernando Pavan, Cristiane Duque, Luis Regasini   +10 more
openaire   +4 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOLIK DAGING BUAH BUNI (Antidesma bunius (L.) Spreng) TERHADAP Staphylococcus aureus ATCC 25922 dan Escherichia coli ATCC 25923

Jurnal Farmasi Sains dan Komunitas, 2014
: The aim of the study was to determine the antibacterial activity of buni skin-pulp ethanolic extract against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922. Profile of antibiotic resistance which is growing among Staphylococcus aureus
Brigitta Lynda Rakasiwi, C.J. Soegihardjo   +1 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Evaluation of antibacterial activity of Pseudomonas species isolated from Pacific white shrimp (Litopenaeus vannamei Boone, 1931) against pathogenic Vibrio spp. [PDF]

بوم‌شناسی آبزیان, 2016
In this research antibacterial activity of Pseudomonas isolates derived from hepatopancreas of Litopenaeus vannamei were evaluated against pathogenic Vibrio spp.
Ramin Karim zadeh, Amir Houshang Bahri, Mohsen Gozari   +2 more
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source