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Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
Nanosilver: An Old Antibacterial Agent with Great Promise in the Fight against Antibiotic Resistance. [PDF]
Kaiser KG+6 more
europepmc +1 more source
The ion-specific increases in membrane permeability with a group of membrane-active antibacterial agents [PDF]
W. Allan Hamilton, R E Jeacock
openalex +1 more source
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef+12 more
wiley +1 more source
Bacteriophage endolysin Ply113 as a potent antibacterial agent against polymicrobial biofilms formed by enterococci and Staphylococcus aureus. [PDF]
Wang J+8 more
europepmc +1 more source
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue+15 more
wiley +1 more source
Susceptibility of Pneumococci and Haemophilus influenzae to Antibacterial Agents [PDF]
Maxwell Finland+3 more
openalex +1 more source