Results 261 to 270 of about 135,613 (288)

Antibacterial Agents

2015
This chapter traces how the modern antibiotic era began with the discoveries of penicillin by Fleming in 1928 and sulfonamides by Domagk in 1932. It lists different classes of antibacterial agents that have been developed for the use in humans.
James S. Lewis, Karen Bush
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ANTIBACTERIAL AGENTS IN PEDIATRICS

Infectious Disease Clinics of North America, 2000
From low birth weight infants to adolescents, physiologic and developmental differences underlie the marked differences in pharmacokinetics and pharmacodynamics of antibacterial agents. Certain diseases, such as cystic fibrosis, also can alter these parameters.
V H, San Joaquin, T L, Stull
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Biaryl isoxazolinone antibacterial agents

Bioorganic & Medicinal Chemistry Letters, 2005
In an era of increasing resistance to classical antibacterial agents, the synthetic oxazolidinone series of antibiotics has attracted much interest. Zyvoxtrade mark was the first oxazolidinone to be approved for clinical use against infections caused by multi-drug resistant Gram-positive bacteria.
Claude A, Quesnelle, Patrice, Gill, Stephan, Roy, Marco, Dodier, Anne, Marinier, Alain, Martel, Lawrence B, Snyder, Stanley V, D'Andrea, Joanne J, Bronson, Marybeth, Frosco, Danielle, Beaulieu, Glen A, Warr, Ken L, Denbleyker, Terry M, Stickle, Hyekyung, Yang, Susan E, Chaniewski, Cheryl A, Ferraro, Dennis, Taylor, John W, Russell, Kenneth S, Santone, Junius, Clarke, Rebecca L, Drain, Jay O, Knipe, Kathleen, Mosure, John F, Barrett   +24 more
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Oxazolidinones: New antibacterial agents

Trends in Microbiology, 1997
The oxazolidinones are a new chemical class of synthetic antibacterial agents that are active orally or intravenously against multidrug-resistant Gram-positive bacteria. Their unique mechanism of action and activity against bacteria that pose therapeutic problems in hospital and community treatments make them promising candidates for antimicrobial ...
C W, Ford, J C, Hamel, D, Stapert, J K, Moerman, D K, Hutchinson, M R, Barbachyn, G E, Zurenko   +6 more
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ANTIBACTERIAL AGENTS IN PEDIATRICS

Infectious Disease Clinics of North America, 1995
The utility of various antibacterial agents for therapy of infectious diseases in children is determined by the unique pharmacokinetics and potential toxicity in children. The important age-related principle of pharmacokinetics is reviewed in the first section of this article; the second section focuses on specific therapeutic agents and their use in ...
J J, LiPuma, T L, Stull
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Antibacterial Agents in Pediatrics

Infectious Disease Clinics of North America, 2009
Antibiotics are among the most frequently used drugs in children. Although antibacterials have been available for decades, many agents have not been studied to assess their safety and efficacy in the pediatric population. This article describes the pharmacologic characteristics and therapeutic use of the most commonly prescribed antibacterials for ...
Susana, Chavez-Bueno, Terrence L, Stull
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Chapter 12. Antibacterial Agents

1990
Publisher Summary The recent studies in antibacterial agents highlight the advances including improved gram-positive, anaerobe, chlamydia activity, and in some cases improved pharmacokinetics in comparison with ciprofloxacin. Major areas of antibiotic research also include the quinolones, β-lactams, glycopeptides, and a variety of other compounds ...
D WHITE, L DAVENPORT
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Antibacterial agents in pediatrics

Infectious Disease Clinics of North America, 2004
Antibiotics are among the most widely prescribed therapeutic agents in children. Several new trends in antibiotic usage for pediatric care have emerged. New mechanisms of antibacterial resistance have required a broader repertoire of antibiotic usage, including new agents directed at multidrug resistance.
Karen L, Bowlware, Terrence, Stull
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Resistance to Antibacterial Agents

1995
There are three major mechanisms whereby bacteria initially susceptible to an antimicrobial agent may acquire the ability to resist the effects of this agent. These include prevention of intracellular drug accumulation, alteration in the target of the drug, and production of a drug-inactivating enzyme.
C C, Sanders, W E, Sanders
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New Benzylidenethiazolidinediones as Antibacterial Agents.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Dirk A, Heerding, Lisa T, Christmann, Tammy J, Clark, David J, Holmes, Stephen F, Rittenhouse, Dennis T, Takata, Joseph W, Venslavsky   +6 more
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