Results 351 to 360 of about 3,637,165 (381)

Promises and failures of gallium as an antibacterial agent.

Future Microbiology, 2014
Gallium has a long history as a diagnostic and chemotherapeutic agent. The pharmacological properties of Ga(III) rely on chemical mimicry; when Ga(III) is exogenously supplied to living cells it can replace Fe(III) within target molecules, thereby ...
F. Minandri, C. Bonchi, E. Frangipani, F. Imperi, P. Visca   +4 more
semanticscholar   +1 more source

Haloemodin as novel antibacterial agent inhibiting DNA gyrase and bacterial topoisomerase I.

Journal of Medicinal Chemistry, 2014
Drug-resistant bacterial infections and lack of available antibacterial agents in clinical practice are becoming serious risks to public health. We synthesized a new class of haloemodins by modifying a traditional Chinese medicine component, emodin.
Feixia Duan, Xiaohong Li, Su-ping Cai, Guang Xin, Yanyan Wang, D. Du, Shiliang He, Baozhan Huang, Xiurong Guo, Hang Zhao, Rui Zhang, Limei Ma, Yan Liu, Qigen Du, Zeliang Wei, Zhihua Xing, Yong Liang, Xiaohua Wu, C. Fan, Chengjie Ji, Dequan Zeng, Qianming Chen, Yang He, Xuyang Liu, Wen Huang   +24 more
semanticscholar   +1 more source

Graphene oxide-silver nanocomposite as a highly effective antibacterial agent with species-specific mechanisms.

ACS Applied Materials and Interfaces, 2013
Recently, graphene oxide (GO) based nanocomposites have raised significant interests in many different areas, one of which being antibacterial agents where sliver nanoparticle (AgNPs) anchored GO (GO-Ag) has shown promising potential.
Jiali Tang, Qian Chen, Ligeng Xu, Shuai Zhang, Liangzhu Feng, Liang Cheng, Huan Xu, Zhuang Liu, Rui Peng   +8 more
semanticscholar   +1 more source

6 The Fluoroquinolone Antibacterial Agents

1990
In summary, the last decade has been a highly fertile and productive period in quinolone medicinal chemistry, resulting in major improvements in potency, antibacterial spectra, oral absorption and pharmacokinetic properties as well as an increased knowledge of the molecular features important to conferring these various properties.
openaire   +2 more sources

Silver-Modified Nano-titania as an Antibacterial Agent and Photocatalyst

, 2014
With the increasing demand for nanomaterials, it is essential that they are produced, where possible, by sustainable or “green” synthesis methods, avoiding environmentally harmful processes and solvents, with the aim of reducing the production of ...
D. Tobaldi, C. Piccirillo, R. Pullar, A. Gualtieri, M. P. Seabra, P. Castro, J. Labrincha   +6 more
semanticscholar   +1 more source

Cutaneous Reactions to Antibacterial Agents

SKINmed: Dermatology for the Clinician, 2002
Antibacterial agents may cause a variety of untoward reactions. Some range from transient, mild erythema to toxic epidermal necrolysis, often resulting in disability and death. Both in vivo and in vitro tests are becoming useful for the diagnosis of the causative agent in drug eruptions.
Joseph A. Witkowski, Lawrence Charles Parish   +1 more
openaire   +3 more sources

Biaryl isoxazolinone antibacterial agents

Bioorganic & Medicinal Chemistry Letters, 2005
In an era of increasing resistance to classical antibacterial agents, the synthetic oxazolidinone series of antibiotics has attracted much interest. Zyvoxtrade mark was the first oxazolidinone to be approved for clinical use against infections caused by multi-drug resistant Gram-positive bacteria.
MaryBeth Frosco, Terry M. Stickle, John F. Barrett, Anne Marinier, Hyekyung Yang, Junius Clarke, Stephan Roy, Susan Chaniewski, Kenneth S. Santone, Patrice Gill, Rebecca L. Drain, Glen A. Warr, John W. Russell, Kathleen W. Mosure, Danielle Beaulieu, Stanley D'andrea, Cheryl Ferraro, Claude A. Quesnelle, Marco Dodier, Alain Martel, Lawrence B. Snyder, Ken Denbleyker, Dennis Taylor, Joanne J. Bronson, Jay O. Knipe   +24 more
openaire   +3 more sources

ANTIBACTERIAL AGENTS IN RENAL FAILURE

Infectious Disease Clinics of North America, 1995
This article provides background information on the pharmacokinetics of antimicrobial agents in patients with normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure.
Mark J. Ingerman, Livornese Ll, Benz Rl, Santoro J   +3 more
openaire   +2 more sources

Chapter 12. Antibacterial Agents

1990
Publisher Summary The recent studies in antibacterial agents highlight the advances including improved gram-positive, anaerobe, chlamydia activity, and in some cases improved pharmacokinetics in comparison with ciprofloxacin. Major areas of antibiotic research also include the quinolones, β-lactams, glycopeptides, and a variety of other compounds ...
David R. White, Lorraine C. Davenport
openaire   +2 more sources

Antibacterial Chemotherapeutic Agents [PDF]

, 1997
Introduction. Sulfonamides, related bacterial folic acid inhibitors, sulfone antibacterials. B-Lactam antibiotics. Tetracycline antibacterials. Aminoglycoside antibacterials. Macrolides antibacterial agents. Quinolone antibacterials. Antibacterial peptides and polypeptides. Anticancer anthracyclines and related antibacterial agents.
openaire   +1 more source