Results 51 to 60 of about 3,533,052 (340)

Antibacterial effect of some eukaryotic sterol biosynthesis inhibitors

Advanced Biomedical Research, 2022
Background: Isoprenoids and their derivatives are building blocks for the synthesis of biomolecules with important biological functions such as cholesterol in eukaryotes and lipid carrier undecaprenol, which is involved in cell wall biosynthesis in ...
Ghasem Arjmand, Mohammad Reza Haeri
doaj   +1 more source

Bacteriocins: Not Only Antibacterial Agents

Probiotics and Antimicrobial Proteins, 2016
This commentary was aimed at shedding light on the multifunction of bacteriocins mainly those produced by lactic acid bacteria. These antibacterial agents were first used to improve food safety and quality. With the increasing antibiotic resistance concern worldwide, they have been considered as viable agents to replace or potentiate the fading ...
Drider, Djamel, Bendali, Farida, Naghmouchi, Karim, Chikindas, Michael L.   +3 more
openaire   +5 more sources

Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli

FEBS Open Bio, EarlyView.
BacA, PgpB, and YbjG phosphatases are involved in undecaprenyl phosphate (C55P) synthesis in Escherichia coli. We analyzed the lipid contents and the gene expression in the gene‐disruption strains. Undecaprenyl diphosphate (C55PP) level increased in the bacA, ybjG double‐disruption strain, but C55P levels were similar in all strains.
Tomotaka Jitsukawa, Yasushi Shigeri, Shingo Fujisaki   +2 more
wiley   +1 more source

Antibacterial Activity and Pharmacokinetic Profile of a Promising Antibacterial Agent: 22-(2-Amino-phenylsulfanyl)-22-Deoxypleuromutilin

Molecules, 2020
A new pleuromutilin derivative, 22-(2-amino-phenylsulfanyl)-22-deoxypleuromutilin (amphenmulin), has been synthesized and proved excellent in vitro and in vivo efficacy than that of tiamulin against methicillin-resistant Staphylococcus aureus (MRSA ...
Xiangyi Zuo, Xi Fang, Zhaosheng Zhang, Zhen Jin, Gaolei Xi, Yahong Liu, Youzhi Tang   +6 more
doaj   +1 more source

Discovery of N-quinazolinone-4-hydroxy-2-quinolone-3-carboxamides as DNA gyrase B-targeted antibacterial agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Emerging drug resistance is generating an urgent need for novel and effective antibiotics. A promising target that has not yet been addressed by approved antibiotics is the bacterial DNA gyrase subunit B (GyrB), and GyrB inhibitors could be effective ...
Wenjie Xue, Yaling Wang, Xu Lian, Xueyao Li, Jing Pang, Johannes Kirchmair, Kebin Wu, Zunsheng Han, Xuefu You, Hongmin Zhang, Jie Xia, Song Wu   +11 more
doaj   +1 more source

Resveratrol—Potential Antibacterial Agent against Foodborne Pathogens

Frontiers in Pharmacology, 2018
Bacterial foodborne pathogens are a significant health burden and the recent emergence of pathogenic resistant strains due to the excessive use of antibiotics makes it more difficult to effectively treat infections as a result of contaminated food ...
D. S. Ma, Loh Teng-Hern Tan, Kok-Gan Chan, W. Yap, Priyia Pusparajah, L. Chuah, L. Ming, T. Khan, Learn‐Han Lee, B. Goh   +9 more
semanticscholar   +1 more source

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen, Henrik Horwitz, Ida M. Heerfordt, Elisabeth Framke, Melinda Magyari   +4 more
wiley   +1 more source

Bacillus anthracis and antibacterial agents [PDF]

Clinical Microbiology and Infection, 2002
Anthrax is one of the oldest threats to humankind, and remains endemic in animals in many parts of the world. Human cases are infrequent, and some result from biological warfare. This review summarizes the current knowledge on the antibacterial activity of available antibiotics. For potential use in the most severe cases of anthrax, antibacterials need
openaire   +3 more sources

Antimicrobial Titanium–Copper Alloys: The Role of Microstructure in Arc‐Melted Compositions

Advanced Engineering Materials, EarlyView.
Copper‐containing titanium alloys show promise in combating orthopedic implant infections. This study explores the influence of heat treatment on Ti‐11.5Cu and Ti‐33Cu alloys, revealing that larger Ti2Cu precipitates (≈5 μm) enhance antimicrobial efficacy through increased surface contact. Results suggest contact sterilization is the primary mechanism,
Daisy Rabbitt, Paraic O’Kelly, Victor M. Villapún, Luke N. Carter, Alexander J. Knowles, Sophie C. Cox   +5 more
wiley   +1 more source

Water-Soluble Ruthenium (II) Complex Derived From Optically Pure Limonene and Its Microencapsulation Are Efficient Tools Against Bacterial Food Pathogen Biofilms: Escherichia coli, Staphylococcus aureus, Enteroccocus faecalis, and Listeria monocytogenes

Frontiers in Microbiology, 2021
Bioactive aminooxime ligands based on optically pure (R)-limonene have been synthesized in two steps. Their ruthenium (II) cationic water-soluble complex was prepared by a reaction between dichloro (para-cymene) ruthenium (II) dimers and aminooxime ...
Simon Khelissa, Yousra El Fannassi, Yousra El Fannassi, Samah Mechmechani, Sakhr Alhuthali, Sakhr Alhuthali, Mohamed Amin El Amrani, Adem Gharsallaoui, Alexandre Barras, Nour-Eddine Chihib   +9 more
doaj   +1 more source