A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen+17 more
wiley +1 more source
Clinicians’ adherence to local antibiotic guidelines for upper respiratory tract infections in the ear, nose & throat casualty department of a public general hospital [PDF]
Background: In Malta, resistance to antibiotics constitutes a major threat to public health. This study aims to assess clinicians’ adherence to local antibiotic guidelines when treating cases of acute otitis media, acute tonsillitis and ...
Caruana Galizia, Sarah+1 more
core
In vitro selective growth-inhibitory effect of 8-hydroxyquinoline on Clostridium perfringens versus Bifidobacteria in a medium containing chicken ileal digesta [PDF]
Clostridium perfringens-induced necrotic enteritis is generally controlled by antibiotics. However, because of increasing antibiotic resistance, other antibacterial agents are required, preferably ones that do not affect the beneficial intestinal ...
Hovorkova, Petra+3 more
core +3 more sources
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie+8 more
wiley +1 more source
Indole-core-based novel antibacterial agent targeting FtsZ
Wenchang Yuan,*,1 Zhiwu Yu,*,2 Weiqi Song,*,3 Yanan Li,4 Zhiyuan Fang,1 Baizhen Zhu,1 Xiaomei Li,1 Hao Wang,5 Wei Hong,6 Ning Sun1,71The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou 510700, People’s Republic ...
Yuan W+9 more
doaj
Background/Aim: The purpose of this in-vitro study was to compare the resin-bonded fixed partial dentures (RBFPD) fabricated using two different structural designs and two different antibacterial adhesive lutting protocols in regard to their resistance ...
Kale Ediz+2 more
doaj +1 more source
Three innovations of next-generation antibiotics: evolvability, specificity, and non-immunogenicity [PDF]
Antimicrobial resistance is a silent pandemic that is being exacerbated by the uncontrolled use of antibiotics. Since the discovery of penicillin, we have been largely dependent on microbe-derived small molecules to treat bacterial infections. However, the golden era of antibiotics is coming to an end as the emergence and spread of antimicrobial ...
arxiv
Study on Activity of Cocoa Ethanolic Extract Against Shigella Dysenteriae [PDF]
Shigella dysenteriae is a gastrointestinal pathogen which shows resistance to antibiotics. A study has been conducted to investigate alternative antibacterial agents, due to the emerging resistance of S.
Isnaini, A. (Alvin)+7 more
core
Antibacterial effect of a new haemostatic agent on oral microorganisms [PDF]
Objective: The purpose of this study was to determine the antibacterial effect of a newly developed haemostatic agent Ankaferd Blood Stopper® (ABS) and Ferric Sulphate (FS) on various oral microorganisms.
Akca, Gülçin+3 more
core +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source