Chemical Profile and Antibacterial Effect of <i>Pimenta dioica</i> Essential Oil Against <i>Ralstonia solanacearum</i> Race 2 Causing Moko Disease on Banana Crop. [PDF]
Martínez-Bolaños L +9 more
europepmc +1 more source
Artificial Intelligence‐Empowered Single‐Cell Phenotyping for Rapid, Automated Pathogen Diagnostics
This work presents an integrated diagnostic platform that combines microfluidic single‐cell bacterial detection with artificial intelligence‐driven analysis for rapid antimicrobial susceptibility testing. Single‐cell phenotyping enables assessment of antibiotic response in only a few cell replication cycles, while AI analysis supports precise bacterial
Sabita Khadka +3 more
wiley +1 more source
Silver nitrate enhances antibacterial effect of colistin against intrinsic colistin resistant <i>Edwardsiella piscicida</i>. [PDF]
Shi Y +7 more
europepmc +1 more source
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan +16 more
wiley +1 more source
Antibacterial effect of various herbal root canal irrigants. [PDF]
N V +7 more
europepmc +1 more source
In an invasive beetle–fungus complex, the mutualist Leptographium procerum induces host HSP83 and modulates Toll‐dependent antifungal immunity. HSP83 mediates two‐tiered control by associating with selected fungal recognition receptors and restraining Dorsal‐driven antimicrobial peptide transcription.
Qingtai Yang +8 more
wiley +1 more source
Identification and expression of a novel antimicrobial peptide Gloverin and its antibacterial effect against Staphylococcus aureus. [PDF]
Lian K +6 more
europepmc +1 more source
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang +17 more
wiley +1 more source
Bovine lactoferrin maintains antibacterial effect against neonatal <i>Escherichia coli</i> septicaemia isolates despite the presence of iron acquisition genes. [PDF]
Mayorga M +3 more
europepmc +1 more source
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu +8 more
wiley +1 more source

