Results 91 to 100 of about 311,813 (210)

Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]

open access: yes, 2016
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core   +1 more source

Scorpion venom peptides enhance immunity and survival in Litopenaeus vannamei through antibacterial action against Vibrio parahaemolyticus

open access: yesFrontiers in Immunology
IntroductionScorpion venom-derived antimicrobial peptides (AMPs) have emerged as promising candidates for combating bacterial infections owing to their potent activity and unique mechanisms of action.
Ling Zeng   +6 more
doaj   +1 more source

Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]

open access: yes, 2016
We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad   +4 more
core   +2 more sources

Antibacterial Mechanisms of Polymyxin and Bacterial Resistance

open access: yesBioMed Research International, 2015
Multidrug resistance in pathogens is an increasingly significant threat for human health. Indeed, some strains are resistant to almost all currently available antibiotics, leaving very limited choices for antimicrobial clinical therapy. In many such cases, polymyxins are the last option available, although their use increases the risk of developing ...
Zhiliang Yu   +4 more
openaire   +2 more sources

Antimicrobial Peptides in Marine Animals and Their Application in Food Preservation

open access: yesShipin gongye ke-ji
Microbial contamination is considered an important contributor to both food spoilage and food safety issues, and the development of new natural antimicrobial agents with broad-spectrum and highly efficient bacterial inhibition has become a hot research ...
Ju CHEN   +10 more
doaj   +1 more source

Antibacterial Activity and Membrane-Disruptive Mechanism of 3-p-trans-Coumaroyl-2-hydroxyquinic Acid, a Novel Phenolic Compound from Pine Needles of Cedrus deodara, against Staphylococcus aureus

open access: yesMolecules, 2016
Recently, we reported that a novel phenolic compound isolated from Cedrus deodara, 3-p-trans-coumaroyl-2-hydroxyquinic acid (CHQA), exhibits a potent antioxidant activity.
Yanping Wu   +6 more
doaj   +1 more source

Self-fluorescent antibiotic MoOx–hydroxyapatite: a nano-theranostic platform for bone infection therapies [PDF]

open access: yes, 2019
Nowadays, the repair of large-size bone defects represents a huge medical challenge. A line of attack is the construction of advanced biomaterials having multifunctional properties.
Baldini, Monica Diana   +6 more
core   +1 more source

Plant-Based ZnO Nanoparticles for Green Nanobiocontrol of a Highly Virulent Bacterial Leaf Blight Pathogen: Mechanistic Insights and Biocompatibility Evaluation

open access: yesNanomaterials
Bacterial leaf blight (BLB), caused by Xanthomonas oryzae pv. oryzae (Xoo), poses a serious threat to rice cultivation. This study presents the green synthesis of zinc oxide nanoparticles (ZnO NPs) using an aqueous leaf extract of the medicinal plant ...
Preeda Chanthapong   +9 more
doaj   +1 more source

Magnesium Oxide Nanoparticles: Effective Agricultural Antibacterial Agent Against Ralstonia solanacearum

open access: yesFrontiers in Microbiology, 2018
Magnesium (Mg) is an essential mineral element for plants and is nontoxic to organisms. In this study, we took advantage of nanotechnologies to systematically investigate the antibacterial mechanisms of magnesium oxide nanoparticles (MgONPs) against the ...
Lin Cai   +5 more
doaj   +1 more source

Chlorogenic Acid Targets Cell Integrity and Virulence to Combat Vibrio parahaemolyticus

open access: yesFoods
Vibrio parahaemolyticus is a primary foodborne pathogen in seafood that endangers consumers’ health. It is vital to develop novel prevention and control strategies due to its extensive transmission and drug resistance.
Huan Liu   +4 more
doaj   +1 more source

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